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KIR2DL4 genetic diversity in a Brazilian population sample: implications for tr...
Weiss, Emiliana [UNESP]; Andrade, Heloisa S. [UNESP]; Lara, Juliana Rodrigues [UNESP]; Souza, Andreia S. [UNESP]; Paz, Michelle A. [UNESP]Made available in DSpace on 2021-06-25T10:53:00Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-06-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); KIR2DL4 is an important immune modulator expressed in natural killer cells; HLA-G is its main ligand. We have characterized the KIR2DL4 genetic diversity by considering the promoter, all exons, and all introns in a highly admixed Brazilian p...
Hla-C genetic diversity and evolutionary insights in two samples from Brazil an...
Souza, Andreia S. [UNESP]; Sonon, Paulin; Paz, Michelle A. [UNESP]; Tokplonou, Léonidas; Lima, Thálitta H. A. [UNESP]; Porto, Iane O. P. [UNESP]Made available in DSpace on 2020-12-12T02:19:59Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; Human leukocyte antigen-C (HLA-C) is a classical HLA class I molecule that binds and presents peptides to cytotoxic T lymphocytes in the cell surface. HLA-C has a dual function because it also interacts with Killer-cell immunoglobulin-like receptors (KIR) receptors expressed in natural killer and T cell...
EVALUATION OF THE HLA-F VARIABILITY IN BRAZIL BY NEXT GENERATION SEQUENCING
Castelli, Erick C. [UNESP]; Lima, Thalitta H. A. [UNESP]; Buttura, Renato V. [UNESP]; Paz, Michelle A. [UNESP]; Porto, Iane O. P. [UNESP]Made available in DSpace on 2018-11-26T15:28:07Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-01-01; UNESP Univ Estadual Paulista, Botucatu, SP, Brazil; Univ Sao Paulo, Sch Med Ribeirao Preto, Ribeirao Preto, SP, Brazil; Fac Filosofia Ciencias & Letras Ribeirao Preto, Ribeirao Preto, SP, Brazil; UNESP Univ Estadual Paulista, Botucatu, SP, Brazil
A FIRST EVALUATION OF THE HLA-A GENE 3 ' UNTRANSLATED REGION DIVERSITY IN BRAZI...
Porto, Iane O. [UNESP]; Lima, Thalitta H. [UNESP]; Paz, Michelle A. [UNESP]; Veiga-Castelli, Luciana C.; Mendes-Junior, Celso T.; Donadi, Eduardo A.Made available in DSpace on 2018-11-26T15:45:24Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-01-01; Sao Paulo State Univ UNESP, Botucatu, SP, Brazil; Univ Sao Paulo, Ribeirao Preto, Brazil; Sao Paulo State Univ UNESP, Botucatu, SP, Brazil
Human leukocyte antigen-G 3’ untranslated region polymorphisms are associated w...
Alves, Cinthia C.; Arruda, Luísa K.P.; Oliveira, Fabíola R.; Massaro, Juliana D.; Aquino, Beatriz J.; Paz, Michelle A. [UNESP]Made available in DSpace on 2018-12-11T17:22:14Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-09-01; Asthma is a genetically complex chronic inflammatory airway disorder, and according to disease pathogenesis, clinical manifestations may vary according to asthma severity. A gene region close to the human leukocyte antigen-G (HLA-G) gene was identified as an independent susceptibility marker for asthma....
HLA-G variability and haplotypes detected by massively parallel sequencing proc...
Castelli, Erick C. [UNESP]; Gerasimou, Petroula; Paz, Michelle A. [UNESP]; Ramalho, Jaqueline [UNESP]; Porto, Iane O.P. [UNESP]Made available in DSpace on 2018-12-11T17:23:21Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-03-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); The HLA-G molecule presents immunomodulatory properties that might inhibit immune responses when interacting with specific Natural Killer and T cell receptors, such as KIR2DL4, ILT2 and ILT4. Thus, HLA-G might influence the outcome of situat...
Hla-mapper: An application to optimize the mapping of HLA sequences produced by...
Castelli, Erick C. [UNESP]; Paz, Michelle A. [UNESP]; Souza, Andréia S. [UNESP]; Ramalho, Jaqueline [UNESP]; Mendes-Junior, Celso TeixeiraMade available in DSpace on 2018-12-11T16:54:16Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-09-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); A challenging task when more than one HLA gene is evaluated together by second-generation sequencing is to achieve a reliable read mapping. The polymorphic and repetitive ...