Made available in DSpace on 2021-07-14T10:36:55Z (GMT). No. of bitstreams: 0 Previous issue date: 2014. Added 1 bitstream(s) on 2021-07-14T11:34:19Z : No. of bitstreams: 1 S2358-04292014000500227.pdf: 492867 bytes, checksum: c03d888175e55803879c4ec5ce6b5e60 (MD5); Harvard Medical School of Public Health, Department of Environmental Health; University of São Paulo, Faculdade de Medicina; Department of Cardiopneu...
-; Objective: To evaluate whether methylene blue (MB) could minimize the effects of ischemia-reperfusion injury in the nonischemic lung on a lung transplantation rodent model. Methods: Forty female Sprague-Dawley rats were divided into 20 donors and 20 recipients. The 20 recipient rats were divided into two groups (n = 10) according to the treatment (0.9% saline vs. 1% MB solutions). All animals underwent unila...
OBJECTIVE: To evaluate the respiratory systems of male and female rats maintained in individually ventilated cages (IVCs) from birth until adulthood. METHODS: Female Wistar rats were housed in individually ventilated cages or conventional cages (CCs) and mated with male Wistar rats. After birth and weaning, the male offspring were separated from the females and kept in cages of the same type until 12 weeks of a...
Made available in DSpace on 2014-09-30T18:18:33Z (GMT). No. of bitstreams: 0 Previous issue date: 2014-07-01Bitstream added on 2014-10-01T14:03:18Z : No. of bitstreams: 1 S1807-59322014000700500.pdf: 399794 bytes, checksum: d6f90151bfc0b0500b0dfff0ef4f5ccd (MD5); OBJECTIVES: Despite the recent success regarding the transplantation of tissue-engineered airways, the mechanical properties of these grafts are not w...
OBJECTIVES: Despite the recent success regarding the transplantation of tissue-engineered airways, the mechanical properties of these grafts are not well understood. Mechanical assessment of a tissue-engineered airway graft before implantation may be used in the future as a predictor of function. The aim of this preliminary work was to develop a noninvasive image-processing environment for the assessment of air...
OBJECTIVE: This study evaluated the performance of lungs that were preserved with different solutions (Celsior, Perfadex or saline) in an ex vivo rat lung perfusion system. METHODS: Sixty Wistar rats were anesthetized, anticoagulated and randomized into three groups (n = 20). The rats were subjected to antegrade perfusion via the pulmonary artery with Perfadex, Celsior, or saline, followed by 6 or 12 hours of i...