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Organotypic endothelial adhesion molecules are key for Trypanosoma brucei tropi...
De Niz, Mariana; Brás, Daniela; Ouarné, Marie; Pedro, Mafalda; Nascimento, Ana M.; Henao Mišíková, Lenka; Franco, Claudio; Figueiredo, Luisa M.Trypanosoma brucei is responsible for lethal diseases in humans and cattle in Sub-Saharan Africa. These extracellular parasites extravasate from the blood circulation into several tissues. The importance of the vasculature in tissue tropism is poorly understood. Using intravital imaging and bioluminescence, we observe that gonadal white adipose tissue and pancreas are the two main parasite reservoirs. We show t...
Date: 2021
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Origin: Repositório da Universidade de Lisboa