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Management of coronary artery disease in patients undergoing transcatheter aort...

Tarantini, Giuseppe; Tang, Gilbert; Nai Fovino, Luca; Blackman, Daniel; Van Mieghem, Nicolas M.; Kim, Won-Keun; Karam, Nicole; Carrilho-Ferreira, Pedro

Significant coronary artery disease (CAD) is a frequent finding in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation (TAVI), and the management of these two conditions becomes of particular importance with the extension of the procedure to younger and lower-risk patients. Yet, the preprocedural diagnostic evaluation and the indications for treatment of significant CAD in TA...


Transcatheter interventions for left-sided valvular heart disease complicated b...

Fraccaro, Chiara; Karam, Nicole; Möllmann, Helge; Bleiziffer, Sabine; Bonaros, Nikolaos; Teles, Rui Campante; Carrilho-Ferreira, Pedro; Chieffo, Alaide

Valvular heart disease (VHD) is one of the most frequent causes of heart failure (HF) and is associated with poor prognosis, particularly among patients with conservative management. The development and improvement of catheter-based VHD interventions have broadened the indications for transcatheter valve interventions from inoperable/high-risk patients to younger/lower-risk patients. Cardiogenic shock (CS) asso...


Usefulness of Routine Fractional Flow Reserve for Clinical Management of Corona...

Van Belle, Eric; Cosenza, Alessandro; Baptista, Sergio Bravo; Vincent, Flavien; Henderson, John; Santos, Lino; Ramos, Ruben; Pouillot, Christophe

Importance: Approximately one-third of patients considered for coronary revascularization have diabetes, which is a major determinant of clinical outcomes, often influencing the choice of the revascularization strategy. The usefulness of fractional flow reserve (FFR) to guide treatment in this population is understudied and has been questioned. Objective: To evaluate the usefulness and rate of major adverse car...


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