2 documents found, page 1 of 1
Human Bone Marrow Mesenchymal Stromal/Stem Cells Regulate the Proinflammatory R...
Laranjeira, Paula; Pedrosa, Mónia; Duarte, Cátia; Pedreiro, Susana; Antunes, Brígida; Ribeiro, Tânia; Santos, Francisco dos; Martinho, AntónioRheumatoid arthritis (RA) is a disabling autoimmune disease whose treatment is ineffective for one-third of patients. Thus, the immunomodulatory potential of mesenchymal stromal/stem cells (MSCs) makes MSC-based therapy a promising approach to RA. This study aimed to explore the immunomodulatory action of human bone marrow (BM)-MSCs on myeloid dendritic cells (mDCs) and monocytes, especially on cytokines/chemok...
Human Bone Marrow Mesenchymal Stromal/Stem Cells Regulate the Proinflammatory R...
Laranjeira, Paula; Pedrosa, Mónia; Duarte, Cátia; Pedreiro, Susana; Antunes, Brígida; Ribeiro, Tânia; Dos Santos, Francisco; Martinho, AntónioRheumatoid arthritis (RA) is a disabling autoimmune disease whose treatment is ineffective for one-third of patients. Thus, the immunomodulatory potential of mesenchymal stromal/stem cells (MSCs) makes MSC-based therapy a promising approach to RA. This study aimed to explore the immunomodulatory action of human bone marrow (BM)-MSCs on myeloid dendritic cells (mDCs) and monocytes, especially on cytokines/chemok...