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Sugarcane straw hemicellulose extraction by autohydrolysis for cosmetic applica...

Pereira, Maria João; Pedrosa, Sílvia S.; Costa, Joana R.; Carvalho, Maria João; Neto, Tânia; Oliveira, Ana L.; Pintado, Manuela; Madureira, Ana Raquel

Sugarcane is a popular crop whose cultivation generates a wide range of by-products. The aim was to optimize the hydrothermal extraction of hemicellulose from sugarcane straw using response-surface methods with a two-factor composite design and to assess its functional qualities. Three process parameters were subject to optimization: solid/liquid ratio (1:6–1:18), temperature (143–186 °C), and extraction time (...


Sugarcane straw as a source of arabinoxylans: optimization and economic viabili...

Costa, Joana R.; Pereira, Maria J.; Pedrosa, Sílvia S.; Gullón, Beatriz; Carvalho, Nelson M. de; Pintado, Manuela E.; Madureira, Ana Raquel

Sugarcane processing produces a significant amount of byproducts in the form of straw and bagasse, which are rich in cellulose, hemicellulose, and lignin. This work aims to provide a valorization approach to sugarcane straw by optimizing a two-step alkaline extraction of arabinoxylans by a response surface methodology to evaluate a potential industrial-scale production. Sugarcane straws were delignified using a...


Valorization of sugarcane by-products through synthesis of biogenic amorphous s...

Costa, Joana R.; Capeto, Ana Paula; Pereira, Carla F.; Pedrosa, Sílvia S.; Mota, Inês F.; Burgal, João da Silva; Pintado, Ana I.; Pintado, Manuela E.

Ashes from sugarcane by-product incineration were used to synthesize silica powders through alkaline hot extraction, followed by ethanol/acid precipitation or the sol–gel method. Both production methods allowed amorphous spherical silica microparticles with sizes ranging from 1–15 μm and 97% purity to be obtained. Water absorption ranged from 135–155 mL/100 g and 150–250 mL/100 g for precipitated silica and sil...


Targetability of hyaluronic acid nanogel to cancer cells: In vitro and in vivo ...

Pedrosa, Sílvia S.; Pereira, Paula; Correia, A.; Gama, F. M.

We have, in previous work developed, characterized and evaluated the biocompatibility of an engineered hyaluronic acid nanogel. Here we assess the targetability of a hyaluronic acid nanogel towards CD44 overexpressing cells, in vitro and in vivo. Results obtained by flow cytometry and confocal fluorescence microscopy shows that nanogel is greatly internalized by non-small cancer lung cells (A549 cells), that ov...


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