23 documents found, page 1 of 3
Fibrose Cardíaca e Mudanças Evolutivas na Função Ventricular Esquerda em Pacien...
Santos,João Bosco de Figueiredo; Gottlieb,Ilan; Tassi,Eduardo Marinho; Camargo,Gabriel Cordeiro; Atié,Jacob; Xavier,Sérgio Salles; Pedrosa,Roberto CouryResumo Fundamento A cardiopatia chagásica (CC) é uma condição de progressão lenta, cujo principal achado histopatológico é fibrose. Objetivos Avaliar se a fibrose cardíaca aumenta ao longo do tempo e se correlaciona com aumento no tamanho do ventrículo esquerdo (CE) e redução na fração de ejeção (FE) na CC crônica. Métodos Estudo retrospectivo que incluiu 20 indivíduos (50% homens; 60±10 anos) com CC crônica qu...
Hereditary transthyretin-mediated amyloidosis with polyneuropathy: baseline ant...
Sequeira,Vanessa Cristina Cunha; Penetra,Maria Alice; Duarte,Lisa; Azevedo,Fernanda Reis de; Sayegh,Raphael Santa Rosa; Pedrosa,Roberto CouryABSTRACT Background: Hereditary transthyretin-mediated (hATTR) amyloidosis with polyneuropathy is a rare, inherited, multisystem, and often fatal disease caused by a variant in transthyretin (TTR) gene. Baseline characteristics of patients, especially anthropometric data, are scarce in the literature, and they are relevant to define effective treatment strategies. Objective: This study aimed to describe baselin...
Effect of combined physical exercise program on improving the functional capaci...
Bavel,Diogo Van; Souza,Wallace Machado Magalhães de; Nery,Yan de Britto; Amorin,Juliana Nascimento; Pedrosa,Roberto Coury; Reis,Michel SilvaAbstract Aims: Patients with Chagas cardiomyopathy (ChC) could have a significant reduction in functional capacity (FC). This study aimed to report the effect of a 24-week combined physical exercise program on the FC of a patient with ChC. Methods: A woman, 44 years old, with positive serology for ChC in stage B2 has submitted the following assessments: i) Physical assessment: ii) Cardiopulmonary exercise test;...
Long-Term Mortality in Cardioinhibitory Carotid Sinus Hypersensitivity Patient ...
Lacerda,Gustavo de Castro; Lorenzo,Andrea Rocha de; Tura,Bernardo Rangel; Santos,Marcela Cedenilla dos; Guimarães,Artur Eduardo CotrimAbstract Background: Cardioinhibitory carotid sinus hypersensitivity (CICSH) is defined as ventricular asystole ≥ 3 seconds in response to 5-10 seconds of carotid sinus massage (CSM). There is a common concern that a prolonged asystole episode could lead to death directly from bradycardia or as a consequence of serious trauma, brain injury or pause-dependent ventricular arrhythmias. Objective: To describe total...
Baseline disease characteristics in Brazilian patients enrolled in Transthyreti...
Cruz,Márcia Waddington; Pinto,Marcus Vinicius; Pinto,Luiz Felipe; Gervais,Renata; Dias,Moisés; Perez,Carlos; Mundayat,Rajiv; Ong,Moh-LimABSTRACT Transthyretin amyloidosis (ATTR) is characterized by the deposit of mutant or wild-type transthyretin that forms amyloid fibrils, which are extracellularly deposited within tissues and organs. Clinical manifestations of familial amyloid polyneuropathy vary according to the mutation, age at onset and geographical location. This study aimed to describe baseline disease characteristics of Brazilian patien...
Diet Quality of patients with chronic Chagas disease in a tertiary hospital: a ...
Castilhos,Mariana Pereira de; Huguenin,Grazielle Vilas Bôas; Rodrigues,Paulo Rogério Melo; Nascimento,Emília Matos do; Pereira,Basílio de BragançaAbstract INTRODUCTION: Nutritional status has been implicated in the modulation of the immune response, possibly augmenting the pathogenesis of Chagas disease (Cd). We evaluated diet quality and nutritional status in adults and elderly patients with chronic Cd in a tertiary hospital. METHODS: A case-control study of Cd patients was conducted, paired for gender, age, and co-morbidities with non-Cd patients. Anth...
Assessment of Autonomic Function by Phase Rectification of RRInterval Histogram...
Nasari Junior,Olivassé; Benchimol-Barbosa,Paulo Roberto; Pedrosa,Roberto Coury; Nadal,JurandirBackground:In chronic Chagas disease (ChD), impairment of cardiac autonomic function bears prognostic implications. Phase‑rectification of RR-interval series isolates the sympathetic, acceleration phase (AC) and parasympathetic, deceleration phase (DC) influences on cardiac autonomic modulation.Objective:This study investigated heart rate variability (HRV) as a function of RR-interval to assess autonomic functi...
Frequency of Cardiovascular Involvement in Familial Amyloidotic Polyneuropathy ...
Queiroz,Márcia Cavalcanti de Campos; Pedrosa,Roberto Coury; Berensztejn,Amanda Cardoso; Pereira,Basílio de Bragança; Nascimento,Emília Matos doBackground:Familial amyloidotic polyneuropathy (FAP) is a rare disease diagnosed in Brazil and worldwide. The frequency of cardiovascular involvement in Brazilian FAP patients is unknown.Objective:Detect the frequency of cardiovascular involvement and correlate the cardiovascular findings with the modified polyneuropathy disability (PND) score.Methods:In a national reference center, 51 patients were evaluated w...
Relação entre Fibrose e Arritmias Ventriculares na Cardiopatia Chagásica sem Di...
Tassi,Eduardo Marinho; Continentino,Marcelo Abramoff; Nascimento,Emília Matos do; Pereira,Basílio de Bragança; Pedrosa,Roberto CouryFundamento: Pacientes com doença de Chagas com alteração segmentar apresentam pior prognóstico independentemente da fração de ejeção ventricular esquerda. A ressonância magnética cardíaca é atualmente o melhor método para detecção de alteração segmentar e para avaliação de fibrose miocárdica. Objetivo: Quantificar a fibrose, por meio do realce tardio, pela ressonância magnética cardíaca, em pacientes com doença...
O carvedilol potencializa o efeito antioxidante das vitaminas E e C na cardiopa...
Budni,Patrícia; Pedrosa,Roberto Coury; Dalmarco,Eduardo Monguilhott; Dalmarco,Juliana Bastos; Frode,Tânia Sílvia; Wilhelm Filho,DaniloFUNDAMENTO: A doença de Chagas continua a ser uma importante doença endêmica no país, sendo o acometimento cardíaco a sua manifestação mais grave. OBJETIVO: Verificar se o uso concomitante de carvedilol potencializará o efeito antioxidante das vitaminas E e C na atenuação do estresse oxidativo sistêmico na cardiopatia chagásica crônica. MÉTODOS: Foram estudados 42 pacientes com cardiopatia chagásica, agrupados ...