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Huntington’s disease presenting as mixed state episode
Corgosinho, Laiane Tábata Souza; Silva, João Antônio Bomfim; Beato, Rogério Gomes; Pedroso, Vinicius Sousa Pietra
Absence of CCR5 increases neutrophil recruitment in severe herpetic encephalitis
Vilela, Márcia Carvalho; Lima, Graciela Kunrath; Rodrigues, David Henrique; Lacerda-Queiroz, Norinne; Pedroso, Vinicius Sousa PietraThe neuroinflammatory response aimed at clearance of herpes simplex virus-1 (HSV-1) plays a key role in the pathogenesis of neuroaxonal damage in herpetic encephalitis. Leukocytes activated in an adaptive immune response access brain tissue by passing through the blood–brain barrier. The chemokine CCL5/RANTES is involved in recruitment of these cells to the brain acting via the receptors CCR1, CCR3 and mainly C...
Paracoccidioidomycosis case series with and without central nervous system invo...
Pedroso, Vinicius Sousa Pietra; Lyon, Ana Cláudia; Araújo, Stanley de Almeida; Veloso, Juliana Márcia Ribeiro; Pedroso, Enio Roberto PietraIntroduction: Paracoccidioidomycosis (PCM) is the most important systemic mycosis in South America. Central nervous system involvement is potentially fatal and can occur in 12.5% of cases. This paper aims to contribute to the literature describing eight cases of neuroparacoccidioidomycosis (NPMC) and compare their characteristics with patients without neurological involvement, to identify unique characteristics...