2 documents found, page 1 of 1
CYP2C19*2 and prognosis after an acute coronary syndrome: Insights from a Portu...
Teixeira, R; Monteiro, P; Marques, G; Pego, J; Lourenço, M; Tavares, C; Reboredo, A; Monteiro, S; Gonçalves, F; Ferreira, MJ; Freitas, M; Ribeiro, GBACKGROUND: Clopidogrel requires oxidation dependent on the cytochrome P450 enzyme 2C19 (CYP2C19) to form its active metabolite. The importance of loss-of-function alleles (particularly CYP2C19*2, 681G>A) in poor platelet response to clopidogrel is well recognized. OBJECTIVE: To investigate the prevalence and prognostic impact of the CYP2C19*2 allele in a local acute coronary syndrome (ACS) population. METHODS:...
Renal artery aneurysm: An endovascular treatment for a rare cause of hypertension
Moreira, N; Pêgo, M; Carvalheiro, V; Agostinho, A; Donato, P; Pego, J; Ferreira, MJ; Providência, LARenal artery aneurysms are a rare cause of secondary hypertension. Endovascular treatment with a polytetrafluoroethylene (PTFE)-coated stent can exclude aneurysms and treat hypertension. We report the case of a 23-year-old man with hypertension diagnosed three years earlier and in whom renal angiography revealed three aneurysms involving the right renal artery. A covered stent was implanted, resulting in succes...