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Identification of biomarkers predictive of metastasis development in early-stag...

Peixoto, Carolina; Lopes, Marta B.; Martins, Marta; Casimiro, Sandra; Sobral, Daniel; Grosso, Ana Rita; Abreu, Catarina; Macedo, Daniela

Publisher Copyright: © 2023, The Author(s).; Colorectal cancer (CRC) is the third most common cancer and the second most deathly worldwide. It is a very heterogeneous disease that can develop via distinct pathways where metastasis is the primary cause of death. Therefore, it is crucial to understand the molecular mechanisms underlying metastasis. RNA-sequencing is an essential tool used for studying the transcr...


Tcox: Correlation-based regularization applied to colorectal cancer survival data

Peixoto, Carolina; Lopes, Marta B.; Martins, Marta; Costa, Luís; Vinga, Susana

This work was partially supported by national funds through Fundacao para a Ciencia e a Tecnologia (FCT) with references PD/BD/139146/2018, IF/00409/2014, UIDB/50021/2020 (INESC-ID), UIDB/50022/2020 (IDMEC), UIDB/04516/2020 (NOVA LINCS), and UIDB/00297/2020 (CMA) and projects PREDICT (PTDC/CCI-CIF/29877/2017) and MATISSE (DSAIPA/DS/0026/2019).; Colorectal cancer (CRC) is one of the leading causes of mortality a...


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