63 documents found, page 1 of 7
The Asymmetrical Face of a Potential Systemic Disease: A Pattern to Recognize
Peixoto, Daniela; Costa , Mariana; Cunha, Rita; Estanqueiro, Paula; Palavra, FilipeParry-Romberg syndrome (PRS) is a rare disorder characterized by a progressive atrophy of the skin, subcutaneous tissue, muscle, and bone of the hemiface, being more common in females. The etiology is unknown, and symptomatology is variable, beginning in the first two decades of life and evolving over 20 years or more. There is no specific treatment, and prognosis depends on the severity of lesions. We report t...
Nature-based hydrogels combined with nanoparticles for bone regeneration
Fernandes, Margarida; Vieira, Mónica; Peixoto, Daniela; Alves, Natália M.; Vieira, MónicaBone is a calcified tissue composed of 60% inorganic compounds, 30% organic compounds, and 10% water. Bone exhibits an intrinsic regenerative capacity, enabling it to heal after fractures or adapt during growth. However, in cases of severe injury or extensive tissue loss, this regenerative capacity becomes insufficient, often necessitating bone graft surgeries using autografts or allografts. Conventional grafti...
Biomateriais e Medicina Regenerativa: o papel do I3Bs numa estratégia de susten...
Silva, Tiago H.; Almeida, Mariana; Peixoto, Daniela; Fernandes, Emanuel Mouta; Alves, N. M.; Reis, R. L.[Excerto] O Instituto de Investigação em Biomateriais, Biodegradáveis e Biomiméticos, I3Bs, é a mais recente Unidade Orgânica da Universidade do Minho, surgindo em março de 2018, tendo sido uma das primeiras Unidades Orgânicas de Investigação criada no âmbito do RJIES (2007) em Universidades públicas Portuguesas. No entanto, a sua história tem origem em 1999, com a criação do Grupo de Investigação 3B’s, dedicad...
Antibacterial properties of photo-crosslinked chitosan/methacrylated hyaluronic...
Gonçalves, Raquel R.; Peixoto, Daniela; Costa, Rui R.; Franco, Albina Ribeiro; Castro, Vânia I. B.; Pires, R. A.; Reis, R. L.; Pashkuleva, I.The current treatments for wounds often fail to produce adequate healing, leaving wounds vulnerable to persistent infections and development of drug-resistant microbial biofilms. New natural-derived nanoparticles were studied to impair bacteria colonization and hinder the formation of biofilms in wounds. The nanoparticles were fabricated through polyelectrolyte complexation of chitosan (CS, polycation) and hyal...
Bioadhesive hyaluronic acid-based hydrogels for spinal cord injury
Duarte, Diogo; Correia, Cátia; Reis, R. L.; Pashkuleva, I.; Peixoto, Daniela; Alves, N. M.Spinal cord injuries (SCI) have devastating physical, psychological, and psycho-social consequences for patients. One challenge of nerve tissue repair is the lack of a natural extracellular matrix (ECM) that guides the regenerating axons. Hyaluronic acid (HA) is a major ECM component and plays a fundamental role in facilitating lesion healing. Herein, we developed HA-based adhesive hydrogels by modification of ...
Como melhorar a saúde das crianças e dos adolescentes? Algumas preocupações, co...
Peixoto, Daniela; Ramos, Joana; Almeida, Paulo; Pimentel, IvaIntrodução: Os cuidados de saúde primários representam o primeiro nível de intervenção dos serviços de saúde. Em idade pediátrica, uma vigilância rigorosa é de extrema importância, pois influencia o crescimento e o bem-estar biopsicossocial, com repercussões na idade adulta. Objetivo: Descrever as principais preocupações sentidas nas consultas de vigilância de saúde infantil e juvenil durante o estágio de cuida...
Five years of universal newborn hearing screening: an incidence study
Leal, Bárbara; Lopes, Ana Cristina; Peixoto, Daniela; Correia, Laura; Almiro, Maria Miguel; Vilar, João; Azevedo, Luísa; Bicho, Maria AdelaideIntroduction: Universal newborn hearing screening (UNHS) is an essential tool for early diagnosis and prognosis of hearing loss. The aims of this study were to estimate the incidence of sensorineural hearing loss (SNHL) in the Baixo Vouga region, to evaluate the importance of first-degree parental consanguinity (FDPC) as a risk factor for hearing loss in the UNHS program of Centro Hospitalar do Baixo Vouga (CHB...
Biocompatible 3D-printed tendon/ligament scaffolds based on polylactic acid/gra...
Silva, Magda Sofia Gonçalves; Gomes, Susana; Correia, Cátia Sofia Palma; Peixoto, Daniela; Vinhas, Carla Adriana Araújo; Rodrigues, Márcia T.Three-dimensional (3D) printing technology has become a popular tool to produce complex structures. It has great potential in the regenerative medicine field to produce customizable and reproducible scaffolds with high control of dimensions and porosity. This study was focused on the investigation of new biocompatible and biodegradable 3D-printed scaffolds with suitable mechanical properties to assist tendon an...
Parental Consanguinity and Risk for Childhood Hearing Loss: A Retrospective Coh...
Leal, Bárbara; Lopes, Ana Cristina; Peixoto, Daniela; Correia, Laura; Almiro, Maria Miguel; Vilar, João; Azevedo, Maria Luísa; Bicho, Maria AdelaideIntroduction: Genetic causes are responsible for half of the cases of hearing loss, most of them being the result of non-syndromic genetic changes resulting from autosomal recessive inheritance. Parental consanguinity might be an indicator to consider in the diagnosis of these cases. The aim of this study was to assess its importance as a risk factor for childhood hearing loss.Material and Methods: A retrospect...
Five years of universal newborn hearing screening: An incidence study
Leal, Bárbara; Lopes, Ana Cristina; Peixoto, Daniela; Correia, Laura; Almiro, Maria Miguel; Vilar, João; Azevedo, Maria Luísa; Bicho, Maria AdelaideIntroduction: Universal newborn hearing screening (UNHS) is an essential tool for early diagnosis and prognosis of hearing loss. The aims of this study were to estimate the incidence of sensorineural hearing loss (SNHL) in the Baixo Vouga region, to evaluate the importance of first-degree parental consanguinity (FDPC) as a risk factor for hearing loss in the UNHS program of Centro Hospitalar do Baixo Vouga (CHB...