13 documents found, page 1 of 2
Interplay between western diet and mammary cancer: data from a chemically-induc...
Silva, J; Azevedo, T; Aires, I; Peixoto, F; Neuparth, MJ; Faustino-Rocha, AI; Duarte, JA; Oliveira, PABackground/Aim: This study aimed to investigate the influence of Western diet on mammary cancer in Wistar female rats, focusing on systemic responses and tumor development. Materials and Methods: Twenty-eight Wistar female rats were acclimatized and divided into four experimental groups (n=7 each): Western diet (WD), Western diet with N-methyl-N- nitrosourea (MNU) administration (WD+MNU), standard diet (CTR), a...
The role of natural compounds in rat mammary cancer: the beneficial effects of ...
Azevedo, Tiago; Silva, J; Faustino-Rocha, Ana I; Valada, A; Anjos, L; Moura, T; Ferreira, T; Santos, M; Pires, MJ; Neuparth, MJ; Peixoto, FBreast cancer is the most diagnosed cancer among women, and a leading cause of death worldwide. Santolina chamaecyparissus L. is a plant with multiple health benefits, includ- ing anticancer and anti-diabetic properties. This study aimed to assess the chemopreven- tive effects of S. chamaecyparissus aqueous ex- tract (SCE) in an animal model of mammary cancer. A total of 28 four-week-old female Wistar rats were...
Cytinus hypocistis (L.) L. extract effects in an animal model of papillomavirus...
Medeiros, C; Silva, AR; Ferreira, T; Barros, L; Neuparth, MJ; Peixoto, F; Bastos, MMSM; Medeiros, R; Gil da Costa, RM; Pires, MJ; Faustino-Rocha, Ana Infections with certain types of papillomavirus, such as the human papillomavirus 16 (HPV16), are associated with the development of preneoplastic lesions and cancers of the anogenital, and head and neck regions. Cytinus hypocistis (L.) L. extracts are composed of substances presenting antiproliferative, antioxidant, anti-inflammatory and antibacterial properties, which might be promising as new therapeutic comp...
ffect of resistance exercise training on blood antioxidant capacity in rats und...
Anjos, J; Santos, S; Anjos, L; Aires, I; Garcias, I; Azevedo, C; Silva, M; Oliveira, PA; Faustino-Rocha, Ana I; Peixoto, FIntroduction: Doxorubicin (DOX) is an efficient chemotherapeutic drug used in the treatment of several types of cancer, such as breast cancer. DOX causes cardiotoxicity that leads to cardiac inflammation and remodeling as a result of oxidative stress and impaired mitochondrial function. Several studies observed a beneficial effect of exercise training on antioxidants, due to upregulation of the activity of some...
Chemopreventive effects of Santolina chamaecyparissus in a rat model of chemica...
Azevedo, T; Faustino-Rocha, Ana I; Silva, J; Valada, A; Anjos, L; Moura, T; Ferreira, R; Santos, M; Pires, MJ; Neuparth, MJ; Peixoto, F; Seixas, FChemopreventive effects of Santolina chamaecyparissus in a rat model of chemically- induced mammary cancer
Characterizing the molecular and physiological changes associated with colorect...
Silva-Reis, R; Faustino-Rocha, Ana I; Castro-Ribeiro, C; Gonçalves, M; Ferreira, T; Pires, MJ; Iglesias- Aguierre, CE; Cortés-Martín, A; Selma, MVCharacterizing the molecular and physiological changes associated with colorectal cancer in wistar rats
Effect of resistance exercise training on blood antioxidant capacity in rats un...
Anjos, J; Santos, SD; Anjos, L; Aires, I; Garcias, I; Azevedo, C; Silva, M; Oliveira, PA; Faustino-Rocha, AI; Peixoto, FIntroduction: Doxorubicin (DOX) is an efficient chemotherapeutic drug used in the treatment of several types of cancer, such as breast cancer. DOX causes cardiotoxicity that leads to cardiac inflammation and remodeling as a result of oxidative stress and impaired mitochondrial function. Several studies observed a beneficial effect of exercise training on antioxidants, due to upregulation of the activity of some...
Chemopreventive effects of Santolina chamaecyparissus in a rat model of chemica...
Azevedo, T; Faustino-Rocha, Ana I; Silva, J; Valada, A; Anjos, L; Moura, T; Ferreira, R; Santos, M; Pires, MJ; Neuparth, MJ; Peixoto, F; Seixas, FChemopreventive effects of Santolina chamaecyparissus in a rat model of chemically- induced mammary cancer.
Effects of resistance training on oxidative stress: data from an animal model o...
Silva, J; Jota-Baptista, C; Silva, MG; Azevedo, T; Valada, A; Anjos, L; Faustino-Rocha, Ana I; Oliveira, PA; Peixoto, F; Duarte, JAEffects of resistance training on oxidative stress: data from an animal model of mammary cancer.
An integrative approach to characterize the early phases of dimethylhydrazine-i...
Silva-Reis, Carla; Castro-Ribeiro, C; Gonçalves, M; Ferreira, T; Pires, MJ; Iglesias-Aguirre, CE; Cortés-Martín, A; Selma, MV; Espín, JCThis study aimed to characterize an animal model of colorectal cancer (CRC) in the early stages of disease development. Twenty-nine male Wistar rats were divided into two control groups (CTRL1 and CTRL2), receiving EDTA–saline injections and two induced groups (CRC1 and CRC2), receiving 1,2-dimethylhydrazine (DMH) injections for seven consecutive weeks. CRC1 and CTRL1 were euthanized at the 11th week, while CRC...