Propolis is a resinous substance collected by honeybees from plant exudates and enriched with beeswax, pollen, and enzymes. Known for its antioxidant, antimicrobial, and anti-aging properties, it has attracted interest for applications in food, nutraceutical, and cosmetic industries. In this work, Portuguese propolis from the Guarda region was characterized to evaluate how different solvents influence extractio...
The epidemiology of tuberculosis has been altered due to the increased use of immunosuppressive therapies (chemotherapy and biologic agents), the human immunodeficiency virus (HIV) epidemic, and the changing migration patterns. Extrapulmonary tuberculosis occurs most often in individuals with HIV infection. Osteoarticular tuberculosis is rare in Western countries, with its diagnosis being performed through cult...
Introduction: Advances in neonatal care have improved the prognosis in extremely preterm infants. The gestational age considered for active treatment has decreased globally. Despite implemented guidelines, several studies show variability in practice. The aim of this study was to understand theperspectives of Portuguese neonatologists and obstetricians regarding the management of extremely preterm infants.Metho...
A presente dissertação discorre sobre o requisito da atividade inventiva da invenção para efeitos de obtenção de patente. O objetivo passa por, numa primeira fase, providenciar ao leitor uma análise histórica e conceptual do direito de patente, assimilando os termos e condições em que o mesmo surgiu, se reproduziu e evoluiu, analisando a respetiva concetualização e requisitos gerais, para, depois, numa segunda ...
A 12 month-old male infant was referred to the paediatric pulmonary unit of our tertiary hospital for further investigation. At the age of 4 months-old, he had been referred by his family doctor to a secondary hospital because of respiratory distress since the first month of life and failure to thrive. At that time, clinical observation revealed an increase in the anteroposterior diameter of the chest, elevated...
Aquatic environmental DNA is increasingly used for biodiversity monitoring, such as surveying threatened and invasive species. Mainstreaming these methods in practi- cal applications, however, still requires significant standardization and optimisation, namely regarding DNA capture methods. Here we evaluated how filter type (standard disc filters vs high-capacity capsules), number of sampling sites, volume of w...
Introduction: Severe peri-intraventricular haemorrhage has been associated with higher mortality and neurodevelopmental impairment. The impact of peri-intraventricular haemorrhage alone (without white matter injury) remains controversial. The aim of this study was to evaluate the influence of severe peri-intraventricular haemorrhage, associated or not with cystic peri-ventricular leukomalacia, on mortality and ...
Introdução: Os sintomas menstruais são condições ginecológicas comuns e frequentemente limitam as atividades diárias de muitas mulheres e levam a problemas no desempenho profissional ou académico. Objetivo: Analisar a influência do exercício na diminuição dos sintomas menstruais em mulheres adultas. Metodologia: A pesquisa foi realizada nas bases de dados PubMed, Web Of Science e PEDro com o intuito de encontra...
A 12 month-old male infant was referred to the paediatric pulmonary unit of our tertiary hospital for further investigation. At the age of 4 months-old, he had been referred by his family doctor to a secondary hospital because of respiratory distress since the first month of life and failure to thrive. At that time, clinical observation revealed an increase in the anteroposterior diameter of the chest, elevated...
This work aimed to characterize the gut and faeces bacterial communities (BC) of Porcellionides pruinosus using high-throughput sequencing. Isopods were collected from the field and kept in laboratory conditions similar to those normally applied in ecotoxicology tests. Faeces and purged guts of isopods (n=3 × 30) were analysed by pyrosequencing the V3-V4 region of 16 S rRNA encoding gene. Results showed that gu...