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Chemical Constituents, Antiproliferative and Antioxidant Activities of Vernonan...
Ramos,Anderson V. G.; Peixoto,Juliana L. B.; Cabral,Márcia R. P.; Amrein,Ana Maria; Tiuman,Tatiana S.; Cottica,Solange M.; Souza,Ilza M. O.Sesquiterpene lactones are an important class of secondary metabolites frequently isolated from Vernonanthura genus that present a variety of biological properties, including antiproliferative activity. Due to the limitation of pharmacological studies on Vernonanthura nudiflora, the aim of this work was to investigate their antioxidant potential and antiproliferative activity against human tumor cells, as well ...
Estudo fitoquímico e avaliação da toxicidade frente a Artemia salina e da ativi...
Domingues,Elaine A.; Nakamura,Celso V.; de Souza,Maria C.; Teixeira,Tatiane S.; Peixoto,Juliana L. B.; Sarragiotto,Maria H.; Vidotti,Gentil J.O estudo fitoquímico das folhas de Calycorectes psidiiflorus (O. Berg) Sobral, Myrtaceae, resultou no isolamento e identificação de: sesquiterpeno [8-hidroxicalameneno (1)], triterpenos [α-amirina (2a) e β-amirina (2b)], flavonóide [3-O-α-ramnopiranosil-7-O-bglucopiranosil canferol (3)], e alcalóide [1,2,3,4-tetraidro-1-metil-β-carbolina (4)]. As estruturas das substâncias isoladas foram elucidadas com base nos...
Evaluation of the molluscicidal and Schistosoma mansoni cercariae activity of C...
Medina,Janaina M.; Peixoto,Juliana L. B.; Silva,Adriano A.; Haraguchi,Shirani K.; Falavigna,Dina L. M.; Zamuner,Maria L. M.; Sarragiotto,Maria H.Lethality of the extracts of Croton floribundus (Euphorbiaceae), a medicinal plant from south Brazil, and of the kaurenoic acid, an isolated compound, and two of its derivatives against adult Biomphalaria glabrata snails, Schistosoma mansoni cercariae and Artemia salina Leach. brine shrimp larvae are reported. Both extracts and the isolated compound showed significant molluscicidal and cercaricidal activities a...
Triterpenic acids from Eugenia moraviana
Lunardi,Inês; Peixoto,Juliana L. B.; Silva,Cleuza C. da; Shuquel,Ivânia T. A.; Basso,Ernani A.; Vidotti,Gentil J.A novel triterpene, characterized as 6alpha-hydroxybetulinic acid, was isolated from the leaves and stems of Eugenia moraviana (Myrtaceae), known in Brazil as Cambuí, together with three known compounds, platanic acid, betulinic acid and beta-sitosterol. Unequivocal ¹H and 13C assignments of 6alpha-hydroxybetulinic acid (3beta,6alpha-dihydroxy-20(29)-lupen-28-oic acid) and platanic acid were undertaken by spect...