9 documents found, page 1 of 1
Monkeypox virus infection in HIV-1- coinfected patients previously vaccinated a...
Brazão, C.; Garrido, P.M.; Alpalhão, M.; Roda, A.; Vieitez-Frade, J.; Ferreira, J.A.; Pelerito, A.; Lopes de Carvalho, I.; Cordeiro, R.; Borrego, M.J.Monkeypox is a zoonotic orthopoxvirus that incidentally causes disease in humans similar to smallpox, although with lower mortality. This virus is endemic to western and central Africa, with outbreaks in occidental countries related to exotic pet trade and international travel. Coincident immunity to monkeypox virus was previously achieved with vaccinia virus vaccination; however, eradicating smallpox and subse...
Outbreak of monkeypox in an STD clinic in Lisbon
Caldeira, M.; Fernandes, C.; Neves, J.; João, A.; Calado, R.; Pinto, A.R.; Borrego, M.J.; Cordeiro, R.; Machado, J.; Pelerito, A.; Lopes de Carvalho, I.We present the preliminary results of the first 43 patients with a definitive diagnosis of human infection with monkeypox virus, from the dermatovenereology department of Hospital Santo António dos Capuchos, Lisbon, in May 2022 [...].
Ongoing monkeypox virus outbreak, Portugal, 29 April to 23 May 2022
Duque, M.P.; Ribeiro, S.; Martins, J.V.; Casaca, P.; Leite, P. P.; Tavares, M.; Mansinho, K.; Duque, L.M.; Fernandes, C.; Cordeiro, R.; Borrego, M.J.Up to 27 May 2022, Portugal has detected 96 confirmed cases of monkeypox. We describe 27 confirmed cases (median age: 33 years (range: 22–51); all males), with an earliest symptom onset date of 29 April. Almost all cases (n = 25) live in the Lisbon and Tagus Valley health region. Most cases were neither part of identified transmission chains, nor linked to travel or had contact with symptomatic persons or with ...
Paralytic Shellfish Poisoning due to ingestion of contaminated mussels: a case r...
Ribeiro, I.; Pelerito, A.; Cordeiro, R.; Vale, P.; Núncio, M.S.; Lopes de Carvalho, I.In Portugal, the potent paralytic shellfish toxins (PSTs) have appeared irregularly since the onset of a national monitoring program for marine biotoxins in 1986. In years where high contamination levels were attained in bivalves, sporadic cases of human poisonings have been recorded, as in 1994 and 2007. The reappearance of high contamination levels led to the appearance of new cases during the autumn of 2018....
Paralytic shellfish poisoning due to ingestion of contaminated mussels: a 2018 ...
Lopes de Carvalho, I.; Pelerito, A.; Ribeiro, I.; Cordeiro, R.; Núncio, M.S.; Vale, P.In Portugal, the potent paralytic shellfish toxins (PSTs) have appeared irregularly since the onset of a national monitoring program for marine biotoxins in 1986. In years where high contamination levels were attained in bivalves, sporadic cases of human poisonings have been recorded, as in 1994 and 2007. The reappearance of high contamination levels led to the appearance of new cases during the autumn of 2018....
Vacinação anti-raiva em humanos: a importância de avaliar a eficácia da vacinaç...
Cordeiro, R.; Almeida Santos, J.; Pelerito, A.; Lopes de Carvalho, I.; Núncio, M.S.A raiva (RABV) é uma doença zoonótica causada pelo vírus do género Lyssavirus. Tanto a RABV animal como a humana são evitáveis pela vacinação. A vacinação préexposição é indicada a indivíduos que viajem para áreas geográficas de risco, para profissionais que manipulem o vírus ou que tenham contacto com animais potencialmente infetados. O esquema de vacinação pré-exposição inclui três doses. No entanto, caso se ...
Biological toxins detection: a rapid diagnosis in an emergency response
Lopes de Carvalho, I.; Cordeiro, R.; Saraiva, M.; Cunha, I.C.; Pelerito, A.; Núncio, M.S.Toxins are chemical substances of biological origin, and they can be considered chemical or biological warfare agents. Four toxins are included in the list of bioterrorism agents: botulinum toxin (BoNT), saxitocin, ricin, and staphylococcal enterotoxin B. BoNT is included in Category A, while the other 3 are considered Category B. Botulism is a potentially fatal disease caused solely by the action of serologica...
Toxinas: o diagnóstico rápido em resposta a emergências
Lopes de Carvalho, I.; Cordeiro, R.; Pelerito, A.; Núncio, M.S.As toxinas são substâncias químicas de origem biológica que causam doença no Homem podendo algumas ser utilizadas como armas biológicas. Na lista de agentes de bioterrorismo estão incluídas quatro toxinas: neurotoxinas botulínica (BoNt), saxitocina, ricina e enterotoxina estafilocócica B (SEB). O botulismo é uma doença potencialmente fatal causada pela ação das neurotoxinas que impedem a libertação de acetilcol...
Tuning the bioactivity of tensioactive deoxy glycosides to structure: antibacte...
Martins, A.; Santos, M.S.; Dias, C.; Serra, P.; Cachatra, V.; Pais, J.; Caio, J.; Teixeira, V.H.; Machuqueiro, M.; Silva, M.S.; Pelerito, A.New octyl/dodecyl 2,6-dideoxy-D-arabino-hexopyranosides have been synthesized by a simple but efficient methodology based on the reaction of glycals with alcohols catalysed by triphenylphosphane hydrobromide, deprotection, regioselective tosylation and reduction. Their surface-active properties were evaluated in terms of adsorption and aggregation parameters and compared with those of 2-deoxy-D-glycosides and 2...