26 documents found, page 1 of 3

Surtos de mpox em Portugal: resposta laboratorial e desafios no controlo da epi...

A infeção mpox, causada pelo vírus monkeypox (MPXV), tornou-se uma emergência global de saúde pública em 2022. Portugal foi um dos primeiros países a confirmar casos de infeção, o que levou à implementação de um sistema de vigilância laboratorial a nível nacional. Este estudo descreve a evolução epidemiológica de mpox em Portugal entre 2022 e 2025 e avalia o desempenho de diferentes tipos de amostras biológicas...

Viral genetics and transmission dynamics in the second wave of mpox outbreak in...

An Overview of Monkeypox Virus Detection in Different Clinical Samples and Anal...

Mpox is a zoonotic disease caused by the Monkeypox virus (MPXV), and since May 2022, tens of thousands of cases have been reported in non-endemic countries. We aimed to evaluate the suitability of different sample types for mpox diagnostic and assess the temporal dynamics of viral load. We evaluated 1914 samples from 953 laboratory-confirmed cases. The positivity rate was higher for lesion (91.3%) and rectal sw...

Demographic and Clinical Characteristics of Mpox Patients Attending an STD Clin...

Mpox is a viral disease caused by the monkeypox virus, which marked the year of 2022 with a global outbreak. While previously considered to be a zoonosis of almost exclusive animal-to-human transmission, the current outbreak has been attributed to human-to-human transmission, particularly sexual transmission. As a new sexually transmissible disease, we studied the epidemiological and clinical features, as well ...

Viral genetic clustering and transmission dynamics of the 2022 mpox outbreak in...

Pathogen genome sequencing during epidemics enhances our ability to identify and understand suspected clusters and investigate their relationships. Here, we combine genomic and epidemiological data of the 2022 mpox outbreak to better understand early viral spread, diversification and transmission dynamics. By sequencing 52% of the confirmed cases in Portugal, we identified the mpox virus sublineages with the hi...

Comparative complete scheme and booster effectiveness of COVID‐19 vaccines in p...

Background: Information on vaccine effectiveness in a context of novel variants of concern (VOC) emergence is of key importance to inform public health policies. This study aimed to estimate a measure of comparative vaccine effectiveness between Omicron (BA.1) and Delta (B.1.617.2 and sub-lineages) VOC according to vaccination exposure (primary or booster). Methods: We developed a case-case study using data on ...

Detection of mpox using polymerase chain reaction from the skin and oropharynx ...

To the Editor: Since early May 2022, 86,746 mpox virus (MPV) infections have been reported worldwide.1,2 However, its in vivo viral kinetics and infectivity remain unclear.3 We conducted a prospective observational study to determine how long MPV remains detectable in skin lesions and the oropharynx. (...)

Viral genetic clustering and transmission dynamics of the 2022 mpox outbreak in...

Pathogen genome sequencing during epidemics enhances our ability to identify and understand suspected clusters and investigate their relationships. Here, we combine genomic and epidemiological data of the 2022 mpox outbreak to better understand early viral spread, diversification and transmission dynamics. By sequencing 52% of the confirmed cases in Portugal, we identified the mpox virus sublineages with the hi...

Comparative complete scheme and booster effectiveness of COVID‐19 vaccines in p...

Background: Information on vaccine effectiveness in a context of novel variants of concern (VOC) emergence is of key importance to inform public health policies. This study aimed to estimate a measure of comparative vaccine effectiveness between Omicron (BA.1) and Delta (B.1.617.2 and sub-lineages) VOC according to vaccination exposure (primary or booster). Methods: We developed a case–case study using data on ...

Human immunodeficiency virus infection may be a contributing factor to monkeypo...

To the Editor: An outbreak of monkeypox has emerged, and more than 13,000 cases have already been confirmed worldwide. In our department, we have 42 confirmed cases so far. All of them are cisgender males presenting with lesions in the genital, perianal, or perioral areas (Fig 1). Interestingly, we observe a disproportionate number of individuals living with the human immunodeficiency virus (HIV). Below, we pre...