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Comprehensive histopathological analysis of gastric cancer in European and Lati...

Martínez-Ciarpaglini, C; Barros, R; Caballero, C; Boggino, H; Alarcón-Molero, L; Peleteiro, B; Ruiz-García, E; Fernandez-Figueroa, E

"Introduction: Gastric cancer (GC) burden is currently evolving with regional differences associated with complex behavioural, environmental, and genetic risk factors. The LEGACy study is a Horizon 2020-funded multi-institutional research project conducted prospectively to provide comprehensive data on the tumour biological characteristics of gastroesophageal cancer from European and LATAM countries. Material a...


The impact of the COVID-19 pandemic in the clinical assistance to breast cancer...

Ribeiro, I; Peleteiro, B; Fougo, JL

Purpose: We aimed to disclose the impact of the pandemic on breast cancer patients in a specialized breast cancer center (BCC). Methods: A total of 501 breast cancer patients with a first appointment in the BCC from April 1st, 2019 to March 31st, 2021 were divided into four consecutive periods of 6 months. Data from the homologous semesters was compared. Patients with an appointment in the BCC during the study ...


The Impact of Cholecystectomy in Patients with Post-Bariatric Surgery Hypoglycemia

Sardão, D; Santos-Sousa, H; Peleteiro, B; Resende, F; Costa-Pinho, A; Preto, J; Lima-da-Costa, E; Freitas, P

Background: Metabolic surgery is the foremost treatment for obesity and its associated medical conditions. Nonetheless, post-bariatric hypoglycemia (PBH) emerges as a prevalent complication. PBH pathophysiology implicates heightened insulin and glucagon-like peptide 1 (GLP-1) levels, with bile acids (BA) contributing to GLP-1 release. A plausible association exists between cholecystectomy and PBH, which is attr...


Comparison of the differential effect of participation in breast cancer screeni...

Laza-Vásquez, C; Rué-Monné, M; Fougo, JL; Peleteiro, B

Objectives The success of a breast cancer screening program is highly dependent on adherence. We aimed to compare the differential effect of participation in breast cancer screening program versus opportunistic screening or symptomatic detection on tumour characteristics. Methods We included women referred to our Breast Centre in 2015–2021: 321 from the breast cancer screening group (group 1) and 422 through op...


Quality Indicators Compliance and Survival Outcomes in Breast Cancer according ...

Osório, F; Barros, AS; Peleteiro, B; Amendoeira, I; Fougo, JL

Simple Summary In this study, we examined how age impacts the outcomes of breast cancer by comparing three age groups: patients 45 years old or younger, patients between 46 and 69 years old, and patients 70 years old or older. Despite similar cancer staging and tumor characteristics among the age groups, the study found that older patients were prone to suboptimal treatment. Older patients also had a lower over...


Local Antibiotic Delivery Ceramic Bone Substitutes for the Treatment of Infecte...

Alegrete, N; Sousa, SR; Peleteiro, B; Monteiro, FJ; Gutierres, M

Aims: the focus of this study is to evaluate if the combination of an antibiotic with a ceramic biomaterial is effective in treating osteomyelitis in an infected animal model and to define which model and protocol are best suited for in vivo experiments of local bone infection treatment. Methods: a systematic review was carried out based on PRISMA statement guidelines. A PubMed search was conducted to find orig...


Surveillance of surgical site infection after colorectal surgery: comprehensive...

Malheiro, RM; Peleteiro, B; Silva, G; Lebre, A; Paiva, JA; Correia, S

Objective:The incidence of surgical site infection (SSI) is highest after colorectal surgery. We assessed the impact of risk factors for SSI using the population attributable fraction (PAF). Design:Retrospective cohort study. Setting:Portuguese hospitals performing regular surveillance. Patients:We identified patients who underwent colorectal procedures in hospitals that reported colorectal surgeries every year...


Hospital context in surgical site infection following colorectal surgery: a mul...

Malheiro, R; Peleteiro, B; Silva, G; Lebre, A; Paiva, JA; Correia, S

"Background Surgical site infections (SSIs) are associated with poor health outcomes. Their incidence is highest after colorectal surgery, with little improvement in recent years. The role of hospital characteristics is undetermined. Aim To investigate whether SSI incidence after colorectal surgery varies between hospitals, and whether such variance may be explained by hospital characteristics. Methods Data wer...


Pet ownership during the first 5 years after breast cancer diagnosis in the NEO...

Lopes-Conceição, L; Peleteiro, B; Araújo, N; Dias, T; Fontes, F; Pereira, S; Lunet, N

Background Although human-animal interactions (HAI) have been associated with health benefits, they have not been extensively studied among cancer patients nor which factors may influence HAI during cancer survivorship. Therefore, this study aims to describe pet ownership in a breast cancer cohort within 5 years post-diagnosis and to identify associated factors. Methods Four hundred sixty-six patients from the ...


Identifying the Profile of Helicobacter pylori-Negative Gastric Cancers: A Case...

Morais, S; Peleteiro, B; Araújo, N; Malekzadeh, R; Ye, W; Plymoth, A; Tsugane, S; Hidaka, A; Hamada, GS; López-Carrillo, L; Zaridze, D; Maximovich, D

Background: The prevalence of Helicobacter pylori-negative gastric cancer (HpNGC) can be as low as 1%, when infection is assessed using more sensitive tests or considering the presence of gastric atrophy. HpNGC may share a high-risk profile contributing to the occurrence of cancer in the absence of infection. We estimated the proportion of HpNGC, using different criteria to define infection status, and compared...


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