3 documents found, page 1 of 1
GO-DACT : a phase 3b randomised, double-blind, placebo-controlled trial of GOli...
Vieira De Sousa, Elsa Cristina; Alves, Pedro; Rodrigues, Ana M.; Teixeira, Filipa; Tavares Costa, José; Bernardo, Alexandra; Pimenta, SofiaObjectives: To assess the efficacy of golimumab in combination with methotrexate (MTX) versus MTX monotherapy in psoriatic arthritis (PsA) dactylitis. Methods: Multicentre, investigator-initiated, randomised, double-blind, placebo-controlled, parallel-design phase 3b trial in 11 Portuguese rheumatology centres. Patients with PsA along with active dactylitis and naive to MTX and biologic disease-modifying antirh...
Using green to cool the grey: Modelling the cooling effect of green spaces with...
Grilo, Filipa; Pinho, Pedro; Aleixo, Cristiana; Catita, Cristina; Silva, Patrícia; Lopes, Nuno; Freitas, Catarina; Santos-Reis, MargaridaThe urban heat island effect creates warmer and drier conditions in urban areas than in their surrounding rural areas. This effect is predicted to be exacerbated in the future, under a climate change scenario. One way to mitigate this effect is to use the urban green infrastructure as a way to promote the cooling island effect. In this study we aimed to model, with a high spatial resolution, how Mediterranean u...
The GO-DACT protocol : a multicentre, randomized, double-blind, parallel-group ...
Vieira de Sousa, Elsa Cristina; Canhao, Helena; Alves, Pedro; Rodrigues, Ana Maria; Teixeira, Filipa; Tavares-Costa, José; Bernardo, AlexandraThe GO-DACT is an investigator-initiated, national, multicentric randomized placebo-controlled double-blinded trial, that assesses dactylitis as primary endpoint. Psoriatic arthritis patients naïve to methotrexate and biologic disease modifying anti-rheumatic drugs, with at least one active dactylitis, were assigned to golimumab in combination with methotrexate or placebo in combination with methotrexate, for 2...