3 documents found, page 1 of 1
Short-Stability Study of Rifaximin-Based Samples
Kogawa, Ana Carolina [UNESP]; Peltonen, Leena; Nunes Salgado, Herida Regina [UNESP]; Chorilli, Marlus [UNESP]Made available in DSpace on 2020-12-11T21:47:22Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-05-01; Background: Rifaximin is an oral antimicrobial with a daily dose ranging from 600 to 800 mg. It is classified as Class IV in the Biopharmaceutic Classification System. Thus, rifaximin-based samples were developed by complexation to beta-cyclodextrin using a phase solubility diagram, and malaxation and d...
Submission of Rifaximin to Different Techniques: Characterization, Solubility S...
Kogawa, Ana Carolina [UNESP]; Peltonen, Leena; Antonio, Selma Gutierrez [UNESP]; Salgado, Hérida Regina Nunes [UNESP]Made available in DSpace on 2019-10-06T16:18:52Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-04-01; Rifaximin, an oral antimicrobial drug, is marketed as 200-mg tablets. The daily dose ranges from 600 mg (1 tablet 3 times a day) to 800 mg (2 tablets twice a day). It is used for a wide range of ages, from adults to children, since it is indicated for the treatment of hepatic encephalopathy, travelers’ ...
Linkage disequilibrium and haplotype homozygosity in population samples genotyp...
Wang, Hui; Lin, Chia-Ho; Service, Susan; Chen, Yuguo; Freimer, Nelson; Sabatti, Chiara; Karayiorgou, Maria; Roos, J. Louw; Pretorious, HermanObjective: Analyze the information contained in homozygous haplotypes detected with high density genotyping. Methods: We analyze the genotypes of ∼2,500 markers on chr 22 in 12 population samples, each including 200 individuals. We develop a measure of disequilibrium based on haplotype homozygosity and an algorithm to identify genomic segments characterized by non-random homozygosity (NRH), taking into account ...