5 documents found, page 1 of 1
SNP typing reveals similarity in Mycobacterium tuberculosis genetic diversity b...
Marques, Isabel; Soares, Patricia; Nebenzahl-Guimaraes, Hanna; Costa, Joao; Miranda, Anabela; Duarte, Raquel; Alves, Adriana; Macedo, RitaHuman tuberculosis is an infectious disease caused by bacteria from the Mycobacterium tuberculosis complex (MTBC). Although spoligotyping and MIRU-VNTR are standard methodologies in MTBC genetic epidemiology, recent studies suggest that Single Nucleotide Polymorphisms (SNP) are advantageous in phylogenetics and strain group/lineages identification. In this work we use a set of 79 SNPs to characterize 1987 MTBC ...
SNP typing reveals similarity in Mycobacterium tuberculosis genetic diversity b...
Lopes, João S.; Marques, Isabel; Soares, Patricia; Nebenzahl-Guimaraes, Hanna; Costa, João; Miranda, Anabela; Duarte, Raquel; Alves, AdrianaHuman tuberculosis is an infectious disease caused by bacteria from the Mycobacterium tuberculosis complex (MTBC). Although spoligotyping and MIRU-VNTR are standard methodologies in MTBC genetic epidemiology, recent studies suggest that Single Nucleotide Polymorphisms (SNP) are advantageous in phylogenetics and strain group/lineages identification. In this work we use a set of 79 SNPs to characterize 1987 MTBC ...
Recrudescent Plasmodium berghei from Pregnant Mice Displays Enhanced Binding to...
Marinho, Claudio R. F.; Neres, Rita; Epiphanio, Sabrina; Goncalves, Ligia A.; Catarino, Manuela Beirao; Penha-Goncalves, CarlosPregnancy-associated malaria (PAM) is associated with placenta pathology and poor pregnancy outcome but the mechanisms that control the malaria parasite expansion in pregnancy are still poorly understood and not amenable for study in human subjects. Here, we used a set of new tools to re-visit an experimental mouse model of pregnancy-induced malaria recrudescence, BALB/c with chronic Plasmodium berghei infectio...
Pregnancy Outcome and Placenta Pathology in Plasmodium berghei ANKA Infected Mi...
Neres, Rita; Marinho, Claudio R. F.; Goncalves, Ligia A.; Catarino, Manuela Beirao; Penha-Goncalves, CarlosPregnancy-associated malaria (PAM) is expressed in a range of clinical complications that include increased disease severity in pregnant women, decreased fetal viability, intra-uterine growth retardation, low birth weight and infant mortality. The physiopathology of malaria in pregnancy is difficult to scrutinize and attempts were made in the past to use animal models for pregnancy malaria studies. Here, we des...
MALARIA RECRUDESCENCE IN MICE PREGNANCY
Neres, Rita; Marinho, Claudio R.; Goncalves, Ligia A.; Catarino, Manuela B.; Penha-Goncalves, Carlos