42 documents found, page 1 of 5
Bioaccessibility Performance of Phenolic Compounds from Red Fruits During Simul...
Bortolini, Débora Gonçalves; Barros, Lillian; Maciel, Giselle Maria; Peralta, Rosane M.; Corrêa, Vanesa G.; Finimundy, Tiane CristineRed fruits are rich in phenolic compounds, particularly anthocyanins, which contribute to their vibrant colors and health benefits. However, anthocyanins are chemically sensitive during digestion, which affects their bioaccessibility. This study evaluated the impact of simulated gastrointestinal digestion on whole red fruits (oral, gastric, intestinal, and colonic phases). Total phenolic content (TPC) ranged fr...
Gastrointestinal digestion of yerba mate, rosemary and green tea extracts and t...
Correa, Vanesa G.; Garcia-Manieri, Jessica Amanda Andrade; Dias, Maria Inês; Pereira, Carla; Mandim, Filipa; Barros, Lillian; Ferreira, Isabel C.F.R.Polyphenolic compounds are common constituents of human and animal diets and undergo extensive metabolism by the gut microbiota before entering circulation. In order to compare the transformations of polyphenols from yerba mate, rosemary, and green tea extracts in the gastrointestinal tract, simulated gastrointestinal digestion coupled with colonic fermentation were used. For enhancing the comparative character...
Characterization and bioactivity of copaiba essential oil carried in a self-nan...
Ames-Sibin, Ana Paula; Chagas, Any C.; Ferreira, Sabrina B.S.; Mandim, Filipa; Finimundy, Tiane C.; Calhelha, Ricardo C.; Peralta, Rosane M.Copaiba essential oil (CEO) is the volatile part of copaiba balsam, which has been topically used for various inflammatory conditions. However, there are some concerns about the CEO safety for oral use. The lipophilic character of CEO also limits its application in the pharmaceutical field. This study prepared a selfnanoemulsifying drug delivery system (SNEDDS) containing CEO and evaluated its toxic effects aga...
Jatoba (Hymenaea courbaril L.) Pod Residue: A Source of Phenolic Compounds as V...
Del Angelo, Gabriela Lucca; Oliveira, Isabela Silva de; Albuquerque, Bianca R.; Kagueyama, Samanta Shiraishi; Silva, Tamires Barlati VieiraThis study aimed at investigating the chemical composition and a selected group of bioactivities of jatoba (Hymenaea courbaril L.) pod residue. An aqueous extract (deionized water; AE) and a hydroethanolic extract (ethanol: deionized water, 70:30 v/v; ETOH) were obtained via maceration. Ten phenolic compounds were characterized via LC-DAD-ESI/MSn: seven procyanidins, two quercetin derivatives and one taxifolin ...
Purple tea: chemical characterization and evaluation as inhibitor of pancreatic...
Silva, Tamires Barlati Vieira; Dias, Maria Inês; Pereira, Carla; Mandim, Filipa; Ivanov, Marija; Soković, Marina; Ferreira, Isabel C.F.R.A variety of the classic green tea plant, Camellia sinensis, was developed and is exclusive to Kenya. Due to high content of anthocyanin polyphenols in its leaves, the beverage obtained from this variety is purple in color and is the origin of the name purple tea. This work had two main purposes. The first one was to identify and quantify the major anthocyanin polyphenols in a hot water aqueous extract of the p...
Mycosterols
Uber, Thaís Marques; Backes, Emanueli; Corrêa, Rúbia C.G.; Corrêa, Vanesa G.; Bracht, Adelar; Peralta, Rosane M.Sterols are amphipathic lipids that play essential roles in the physiology of eukaryotic organisms in general. The fungal sterols are collectively known as mycosterols and they exert numerous physiological functions. For humans, the interest on this class of compounds relies heavily on the fact that they can promote health benefits. For this reason, fungal extracts rich in sterols of various forms are valuable ...
Exploring the α-amylase-inhibitory properties of tannin-rich extracts of Cytinu...
Correa, Vanesa G.; Garcia-Manieri, Jéssica A.A.; Silva, Ana Rita; Backes, Emanueli; Corrêa, Rúbia C.G.; Barros, Lillian; Bracht, AdelarCytinus hypocistis (L.) L. is an edible parasitic plant that grows within the roots of its host. In addition to its use as famine food in the past, it is also tradidionally used for treating several illnesses such as intestinal problems, inflammations, tumors, and bleeding. This species is rich in hydrolysable tannins, compounds often associated with inhibiting starch digestion. Therefore, the present work inve...
Overproduction of laccase by trametes versicolor and Pycnoporus sanguineus in f...
Backes, Emanueli; Kato-Schwartz, Camila Gabriel; Oliveira Junior, Verci A. de; Uber, Thaís Marques; Santos, Luís F. O. dos; Corrêa, Rúbia C.G.The effect of farnesol, a sesquiterpene alcohol, on the production of laccases by Trametes versicolor and Pycnoporus sanguineus in pineapple waste solid-state fermentation was evaluated. Extracellular laccase production reached a maximum of 77.88 5.62 U/g (236% above control) in farnesol-induced cultures of T. versicolor on the 17th day, whereas in a similar P. sanguineus culture, a maximal laccase activity of ...
Potential of plant extracts in targeting SARS-CoV-2 main protease: an in vitro ...
Araujo, Ingrid Garcia de; Pattaro-Junior, Jose Renato; Barbosa, Cecilia Gomes; Philippsen, Gisele Strieder; Silva, Ana Rita; Ioshino, Rafaella SayuriThe deaths caused by the covid-19 pandemic have recently decreased due to a worldwide effort in vaccination campaigns. However, even vaccinated people can develop a severe form of the disease that requires ICU admission. As a result, the search for antiviral drugs to treat these severe cases has become a necessity. In this context, natural products are an interesting alternative to synthetic medicines used in d...
A critical appraisal of the most recent investigations on the hepatoprotective ...
Garcia-Manieria, Jéssica A.A.; Correa, Vanesa G.; Backes, Emanueli; Sa-Nakanishi, Anacharis Babeto de; Bracht, Lívia; Comar, Jurandir FernandoConventional treatments for liver diseases are often burdened by side effects caused by chemicals. For minimizing this problem, the search for medicines based on natural products has increased. The objective of this review was to collect data on the potential hepatoprotective activity of plants of the Brazilian native flora. Special attention was given to the modes of extraction, activity indicators, and identi...