2 documents found, page 1 of 1
Mycotoxins in Rice Correlate with Other Contaminants? A Pilot Study of the Port...
Silva, Liliana; Pereira, André; Duarte, Sofia; Pedro, Inês; Perdigão, Catarina; Silva, Alexandra; Lino, Celeste M.; Almeida, Anabela; Pena, AngelinaRice is the second most important cereal crop and is vital for the diet of billions of people. However, its consumption can increase human exposure to chemical contaminants, namely mycotoxins and metalloids. Our goal was to evaluate the occurrence and human exposure of aflatoxin B1 (AFB1), ochratoxin A (OTA), zearalenone (ZEN), and inorganic arsenic (InAs) in 36 rice samples produced and commercialized in Portu...
The impact of the genetic risk factor BIN1 to Alzheimer’s disease development
Perdigão, Catarina" Alzheimer’s disease (AD) was identified more than a century ago. Yet, there is still no cure and the mechanisms behind the most common form of AD (late-onset, LOAD) are still an open question. BIN1 was the second gene most frequently associated with LOAD. Bin1 depletion has been linked with AD earliest pathomechanisms: increased beta-amyloid (Aβ) accumulation, endosomal abnormalities, and synaptic defects. Se...