5 documents found, page 1 of 1
Prognostic Factors Associated with Disability in a Cohort of Neuromyelitis Opti...
Moura, João; Samões, Raquel; Sousa, Ana Paula; Figueiroa, Sónia; Mendonça, Teresa; Abreu, Pedro; Guimarães, Joana; Melo, Claúdia; Sousa, RaquelIntroduction: Neuromyelitis optica spectrum disorders (NMOSD) and MOG-associated disease (MOGAD) are an increasingly recognized group of demyelinating disorders of the central nervous system. Previous studies suggest that prognosis is predicted by older age at onset, number of relapses, the severity of the first attack and autoantibody status. Objective: To study prognostic factors associated with disability pr...
Diagnostic delay of multiple sclerosis in a Portuguese population
Aires, Ana; Barros, Ariana; Machado, Célia; Fitas, Diogo; Cação, Gonçalo; Pedrosa, Rui; Cerqueira, João José; Perdigão, Sandra; Silva, Ana MartinsIntroduction: Multiple sclerosis is a chronic inflammatory disease, in which a diagnostic delay could reduce the available therapeutic options. Therefore, it is important to monitor the time to diagnosis and understand factors that may potentially reduce it. The objective of this study was to determine the time between the first symptoms and the diagnosis of multiple sclerosis and which factors may contribute t...
Diagnostic Delay of Multiple Sclerosis in a Portuguese Population
Aires, Ana; Barros, Ariana; Machado, Célia; Fitas, Diogo; Cação, Gonçalo; Pedrosa, Rui; Cerqueira, João; Perdigão, Sandra; Silva, Ana Martins daIntroduction: Multiple sclerosis is a chronic inflammatory disease, in which a diagnostic delay could reduce the available therapeutic options. Therefore, it is important to monitor the time to diagnosis and understand factors that may potentially reduce it. The objective of this study was to determine the time between the first symptoms and the diagnosis of multiple sclerosis and which factors may contribute t...
Monotonic and Cyclic Behavior of DIN 34CrNiMo6 Tempered Alloy Steel
Branco, Ricardo; Costa, José D. M.; Antunes, Fernando V.; Perdigão, SandraThis paper aims at studying the monotonic and cyclic plastic deformation behavior of DIN 34CrNiMo6 high strength steel. Monotonic and low-cycle fatigue tests are conducted in ambient air, at room temperature, using standard 8-mm diameter specimens. The former tests are carried out under position control with constant displacement rate. The latter are performed under fully-reversed strain-controlled conditions, ...
Guillain-Barré syndrome.
Fonseca, Teresa; Cardoso, Teresa; Perdigão, Sandra; Sarmento, António; Morgado, Rui; Costa, Maria ManuelaGuillain-Barré syndrome (GBS) is an autoimmune disease that leads to an axonal demyelination and/or degeneration of peripheral nerves through molecular mimicry. The usual pattern is an ascending areflexic motor paralysis with a distinct cerebral-spinal fluid (CSF) showing elevated protein level without accompanying pleocytosis. Diagnosis is essentially clinical, but the CSF studies and electrodiagnostic feature...