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Abdominal Hypoperfusion and Acute Kidney Injury in the Critically Ill Patient w...

Pereira, Rui; Lopes, Diogo; Machado, Sara Brandão; Val-Flores, Luís; Caeiro, Fernando; Perdigoto, Rui; Marcelino, Paulo Alexandre; Saliba, Faouzi

Background: Reduced abdominal perfusion pressure (APP) is an underdiagnosed potential pathophysiological mechanism for acute kidney injury (AKI) in the patient with liver cirrhosis and ascites. This study aimed to analyze the prevalence of abdominal hypoperfusion (AhP) (APP <60 mm Hg) and the impact of APP on AKI in critically ill patients with liver cirrhosis. Methods: This was a post hoc analysis from a prosp...


Carbapenem-Resistant Enterobacteriaceae Colonization or Infection Was Not Assoc...

Caria, João; Gonçalves, Ana C.; Cristóvão, Gonçalo; Carlos, Maria; Magalhães, Sara; Almeida, Vasco; Moreno, Fernanda; Mateus, Élia; Pinheiro, Hélder

Publisher Copyright: © 2024 The Author(s). Published by S. Karger AG, Basel.; Introduction: Carbapenem-resistant Enterobacteriaceae (CRE) epidemiology among liver transplant (LT) recipients is variable. We studied the impact of CRE colonization and infection on LT recipients' outcomes. Methods: This observational cohort study included consecutive adult LT recipients between January 2019 and December 2020 at Cur...


Alcohol Consumption Post-Liver Transplantation

Chálim Rebelo, Carolina; Félix, Catarina; Cardoso, Filipe S.; Bagulho, Luis; Sousa, Monica; Mendes, Milena; Glória, Helena; Mateus, Élia; Mega, Inês

Publisher Copyright: © 2022 The Author(s). Published by S. Karger AG, Basel. This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC). Usage and distribution for commercial purposes requires written permission.; Background: Listing patients with alcohol-associated liver disease (ALD) for liver transplant (LT) remains challenging especially due to the ris...


Acute-on-Chronic Liver Failure Remains a Minor Indication for Liver Transplant ...

Cardoso, Filipe S.; Perdigoto, Rui; Lamelas, Jorge; Coelho, João S.; Pinto Marques, Hugo; Bagulho, Luis


Abdominal perfusion pressure in critically ill cirrhotic patients

Pereira, Rui Antunes; Esteves, André F.; Cardoso, Filipe S.; Perdigoto, Rui; Marcelino, Paulo; Saliba, Faouzi

Funding Information: The authors of this study would like to thank the entire nursing and medical staff of the intensive care unit, Unidade de Cuidados Intensivos Polivalente 7, at Hospital de Curry Cabral, for their fundamental work in this study, and the “Centro de Investigação”, at Centro Hospitalar Universitário Lisboa Central, for their support. Publisher Copyright: © 2023, The Author(s).; In critical pati...


Continuous passive paracentesis versus large-volume paracentesis in the prevent...

Pereira, Rui Antunes; Virella, Daniel; Perdigoto, Rui; Marcelino, Paulo; Saliba, Faouzi; Germano, Nuno

Funding Information: The authors would like acknowledge and thank the nursing and medical staff at Unidade de Cuidados Intensivos Polivalente 7 (UCIP7), Hospital Curry Cabral, CHULC, for their substantial work and cooperation in this project, as well as Luís Horta, PhD, Ana Luisa Papoila, PhD, and Marta Alves, M.Sc., at the CHULC Research Center for their collaboration and support. Publisher Copyright: © 2023, ...


The Impact of Donor Risk Index, Recipients' and Operative Characteristics on Po...

Cardoso, Filipe S.; Bagulho, Luis; Coelho, João S.; Lamelas, Jorge; Mateus, Élia; Mendes, Milena; Glória, Helena; Ribeiro, Vasco; Mega, Raquel

Publisher Copyright: © 2022; Background and Aims: The donor risk index (DRI) quantifies donor-related characteristics potentially associated with increased risk of early graft failure. We aimed to assess the impact of the DRI, recipient and perioperative factors on post liver transplant (LT) outcomes. Methods: This was a single-center retrospective cohort study including all adult (≥18 years) patients who under...


A Gene Expression Signature to Select Hepatocellular Carcinoma Patients for Liv...

Pinto-Marques, Hugo; Cardoso, Joana; Silva, Sílvia; Neto, João L; Gonçalves-Reis, Maria; Proença, Daniela; Mesquita, Marta; Manso, André; Carapeta, Sara

Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc.; OBJECTIVE: To propose a new decision algorithm combining biomarkers measured in a tumor biopsy with clinical variables, to predict recurrence after liver transplantation (LT). SUMMARY BACKGROUND DATA: Liver cancer is one of the most frequent causes of cancer-related mortality. LT is the best treatment for hepatocellular carcinoma (HCC) pa...


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