19 documents found, page 1 of 2
Machine learning classification of consumption habits of creatine supplements i...
Magalhães, Patrícia C.; Encarnação, Samuel; Miguel Forte, Pedro; de Araújo Teixeria, José Eduardo; Monteiro, A. M.; Barbosa, Tiago M.; Pereira, Ana M.The aim is to identify usage patterns and the main factors that influence creatine supplementation, providing a basis for future educational interventions and recommendations for safe and effective use. The study was applied to gym goers in Bragança, where a QR code for a survey was released. 158 people participated, 65 non-consumers of creatine supplementation (37.34% men; 22.78% women) and 95 consumers (15.19...
An eco-friendly and up-scalable approach to extract canthaxanthin from yeast cells
Pereira, Ana M.; Durão, Joana; Pereira, Joana Odila; Ferreira, Carlos; Faustino, Margarida; Oliveira, Ana Sofia; Pereira, Carla F.; Pintado, Manuela E.Canthaxanthin is a naturally occurring ketocarotenoid pigment present in plants, algae, bacteria and some fungi. In addition to its coloring role, canthaxanthin has an excellent antioxidant activity, thus having additional market demands in the feed, food, cosmetic and pharmaceutical industries. Canthaxanthin can be directly isolated from its natural source or produced by chemical synthesis, but these strategie...
UCRAID (Ukrainian Citizen and refugee electronic support in Respiratory disease...
Bousquet, Jean; Samolinski, Boleslaw; Kaidashev, Igor; Maurer, Marcus; Roche, Nicolas; Sousa-Pinto, Bernardo; Kurchenko, Andrii; Stepanenko, RomanEight million Ukrainians have taken refuge in the European Union. Many have asthma and/or allergic rhinitis and/or urticaria, and around 100,000 may have a severe disease. Cultural and language barriers are a major obstacle to appropriate management. Two widely available mHealth apps, MASK-air® (Mobile Airways Sentinel NetworK) for the management of rhinitis and asthma and CRUSE® (Chronic Urticaria Self Evaluat...
Comparative analysis of mannans extraction processes from spent yeast saccharom...
Faustino, Margarida; Durão, Joana; Pereira, Carla F.; Oliveira, Ana Sofia; Pereira, Joana Odila; Pereira, Ana M.; Ferreira, Carlos; Pintado, Manuela E.Mannans are outstanding polysaccharides that have gained exponential interest over the years. These polysaccharides may be extracted from the cell wall of Saccharomyces cerevisiae, and recovered from the brewing or synthetic biology industries, among others. In this work, several extraction processes—physical, chemical and enzymatic—were studied, all aiming to obtain mannans from spent yeast S. cerevisiae. Thei...
A step for the valorization of spent yeast through production of iron–peptide c...
Ferreira, Carlos; Pereira, Carla F.; Oliveira, Ana Sofia; Faustino, Margarida; Pereira, Ana M.; Durão, Joana; Pereira, Joana Odila; Pintado, Manuela E.Given the importance of iron in human nutrition and the significance of waste and by-product valorisation in a circular economy environment, we investigated the effects of protein and iron concentration on the production yield of iron–peptide complexes from spent Saccharomyces cerevisiae. For this purpose, different amounts of protein and iron were used in the complexation process. The results have shown that h...
Profiling persistent asthma phenotypes in adolescents: A longitudinal diagnosti...
Amaral, Rita; Jácome, Cristina; Almeida, Rute; Pereira, Ana M.; Alves-Correia, Magna; Mendes, Sandra; Rodrigues, José C.; Carvalho, Joana; Araújo, LuísWe aimed to identify persistent asthma phenotypes among adolescents and to evaluate longitudinally asthma-related outcomes across phenotypes. Adolescents (13–17 years) from the prospective, observational, and multicenter INSPIRERS studies, conducted in Portugal and Spain, were included (n = 162). Latent class analysis was applied to demographic, environmental, and clinical variables, collected at a baseline med...
Protein-based films functionalized with a truncated antimicrobial peptide seque...
da Costa, André; Pereira, Ana M.; Sampaio, Paula; Rodriguez-Cabello, Jose Carlos; Gomes, Andreia C; Casal, Margarida; Machado, RaulThe increasing bacterial resistance to antibiotics is driving strong demand for new antimicrobial biomaterials. This work describes the fabrication of free-standing films exhibiting antimicrobial properties by combining, in the same polypeptide chain, an elastin-like recombinamer comprising 200 repetitions of the pentamer VPAVG (A200) and an 18-amino-acid truncated variant of the antimicrobial peptide BMAP-28, ...
ECM-enriched alginate hydrogels for bioartificial pancreas: an ideal niche to i...
Crisóstomo, Joana; Pereira, Ana M.; Bidarra, Sílvia J.; Gonçalves, Ana C.; Granja, Pedro L.; Coelho, Jorge Fj; Barrias, Cristina C; Seiça, RaquelIntroduction: The success of a bioartificial pancreas crucially depends on ameliorating encapsulated beta cells survival and function. By mimicking the cellular in vivo niche, the aim of this study was to develop a novel model for beta cells encapsulation capable of establishing an appropriate microenvironment that supports interactions between cells and extracellular matrix (ECM) components. Methods: ECM compo...
Comparison of hypothesis- and data-driven asthma phenotypes in NHANES 2007–2012...
Amaral, Rita; Pereira, Ana M.; Jacinto, Tiago; Malinovschi, Andrei; Janson, Christer; Alving, Kjell; Fonseca, João A.Half of the adults with current asthma among the US National Health and Nutrition Examination Survey (NHANES) participants could be classified in more than one hypothesis-driven phenotype. A data-driven approach applied to the same subjects may allow a more useful classification compared to the hypothesis-driven one. To compare previously defined hypothesis-driven with newly derived data-driven asthma phenotype...
Disentangling the heterogeneity of allergic respiratory diseases by latent clas...
Amaral, Rita; Bousquet, Jean; Pereira, Ana M.; Araújo, Luís M.; Sá‐Sousa, Ana; Jacinto, Tiago; Almeida, Rute; Delgado, Luís; Fonseca, João A.Background Refined phenotyping of allergic diseases may unravel novel phenotypes. Conjunctivitis as an independent disorder has never been approached. Aim To identify distinct classes of allergic respiratory diseases using latent class analysis (LCA) and distinguish each class using classification and regression tree (CART) analysis. Methods Seven hundred and twenty‐eight adults from the Portuguese general popu...