3 documents found, page 1 of 1
Neurometabolic profiles of autism spectrum disorder patients with genetic varia...
Vilela, Joana; Pereira, Andreia C.; Violante, Inês R.; Mouga, Susana; Rasga, Célia; Santos, João Xavier; Martiniano, Hugo; Marques, Ana RitaAutism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by impaired social interaction, and restricted and repetitive patterns of behavior. ASD presents as a clinical spectrum, with variable levels of severity and multiple co-occurring conditions. The etiology of ASD may involve hundreds of genes and there is evidence that neurotransmitter and synaptic (NS) pathways are implicated. Proton...
Exploratory evidence for differences in GABAergic regulation of auditory proces...
Huang, Qiyun; Velthuis, Hester; Pereira, Andreia C.; Ahmad, Jumana; Cooke, Samuel F.; Ellis, Claire L.; Ponteduro, Francesca M.; Puts, Nicolaas A. J.Altered reactivity and responses to auditory input are core to the diagnosis of autism spectrum disorder (ASD). Preclinical models implicate ϒ-aminobutyric acid (GABA) in this process. However, the link between GABA and auditory processing in humans (with or without ASD) is largely correlational. As part of a study of potential biosignatures of GABA function in ASD to inform future clinical trials, we evaluated...
A neuronal theta band signature of error monitoring during integration of facia...
Dias, Camila; Costa, Diana M.; Sousa, Teresa; Castelhano, João; Figueiredo, Verónica; Pereira, Andreia C.; Castelo Branco, MiguelError monitoring is the metacognitive process by which we are able to detect and signal our errors once a response has been made. Monitoring when the outcome of our actions deviates from the intended goal is crucial for behavior, learning, and the development of higher-order social skills. Here, we explored the neuronal substrates of error monitoring during the integration of facial expression cues using electr...