179 documents found, page 1 of 18
Study of additive manufacturing intrinsic defects on fatigue life of Ti-6Al-4V †
Ribeiro Cardoso Martins Morgado, Teresa Leonor; Alves, João; Pereira, António; Pereira, Manuel; Martins, Rui F.The present work presents a new approach to studying the structural integrity of a Ti-6Al-4V alloy obtained by Selective Laser Melting (SLM). This approach is based on the intrinsic addictive manufacturing defects analysis obtained by nanotomography, the experimental S-N curve, and the small crack growth Murakami and Endo model. Also, two counting methods of 3D manufacturing intrinsic defects were considered. T...
Rational Design of Cost-Effective 4-Styrylcoumarin Fluorescent Derivatives for ...
Eustáquio, Raquel; Ramalho, João Paulo; Caldeira, Ana Teresa; Pereira, AntónioFluorescent labels are key tools in a wide range of modern scientific applications, such as fluorescence microscopy, flow cytometry, histochemistry, direct and indirect immunochemistry, and fluorescence in situ hybridization (FISH). Small fluorescent labels have important practical advantages as they allow maximizing the fluorescence signal by binding multiple fluorophores to a single biomolecule. At present, t...
New 4-styrylcoumarin Derivatives as Potentials Fluorescent Labels for Biomolecu...
Eustáquio, Raquel; Caldeira, Ana Teresa; Arantes, Sílvia; Candeias, António; Pereira, AntónioFluorescence microscopy is a highly sensitive imaging technique used in various scientific fields such as cellular biology, environmental sciences, medicine, and pharmacy. It offers the advantage of using multiple fluorescent labels to visualize different biomolecules and generate multicolored images for identifying specific components within complex biomolecular structures and studying their interactions. Thes...
Affordable Small Molecules as Promising Fluorescent Labels for Biomolecules
Eustáquio, Raquel; Ramalho, João Paulo; Arantes, Sílvia; Candeias, António; Caldeira, Ana Teresa; Pereira, AntónioFluorescent labels, commonly used in highly sensitive analytical techniques for detecting and tracking biomolecules in critical fields like cellular biology, medicine, medicinal chemistry, and environmental science, are currently too expensive for routine use in standard applications, with most exhibiting small Stokes shifts. This limitation underscores the potential of 4-diethylaminobenzaldehyde derivatives as...
New 4-styrylcoumarin derivatives as potentials fluorescent labels for biomolecu...
Eustáquio, Raquel; Caldeira, Ana Teresa; Arantes, Sílvia; Candeias, António; Pereira, AntónioCurrently, fluorescence microscopy is one of the highly sensitive imaging techniques that allow visualize, detect, and track biomolecules in analytical studies in many important scientific areas as cellular biology, environmental sciences, medicine, pharmacy, among others. One of the great advantages of fluorescence microscopy is the possibility to use several fluorescent labels to detect different biomolecules...
Synthesis of new inexpensive fluorescent water-soluble amine-reactive reagents ...
Eustáquio, Raquel; Caldeira, Ana Teresa; Arantes, Sílvia; Candeias, António; Pereira, AntónioCultural heritage assets are being continuously submitted to physical, chemical and biological degradation. Biodegradation is the major factor for their deterioration, with microorganisms being of critical importance due to their metabolism and proliferation. In this context, it is frequently necessary identify and locate individual microorganisms and detect small amounts of biomolecules, as proteins, to know, ...
Inexpensive small molecules as promising fluorescent labels for biomolecules.
Eustáquio, Raquel; Ramalho, João Paulo; Caldeira, Ana Teresa; Pereira, AntónioFluorescent labels are indispensable in various modern scientific applications, including direct and indirect immunochemistry, fluorescence microscopy, histochemistry, flow cytometry and fluorescence in situ hybridization (FISH) [1,2]. Small fluorescent labels offer significant practical benefits, enabling the optimization of fluorescence signals through the attachment of multiple fluorophores to a single biomo...
Synthetic image generation for effective deep learning model training for ceram...
Gaspar, Fábio; Daniel Carreira; Rodrigues, Nuno; Miragaia, Rolando; Ribeiro, José; Costa, Paulo; Pereira, AntónioIn the rapidly evolving field of machine learning engineering, access to large, high-quality, and well-balanced labeled datasets is indispensable for accurate product classification. This necessity holds particular significance in sectors such as the ceramics industry, in which effective production line activities are paramount and deep learning classification mechanisms are particularly relevant for streamlini...
Academic Primary Care Units: From Dream to Reality
Correia, Gil; Pereira, António; Bulhões, Cláudia; Outeirinho, Conceição; Prazeres, Filipe; Rosendo, Inês; Antunes, José Pedro; Monteiro, Luísn/a.; n/d.
Nurse Managers as Promoters of Health Literacy Supported by Information Systems
Santos, Nuno; Matias, Sílvia; Pereira, António; Pinto, Carolina; Oliveira, Rafael; Domingues, Sandra; Santos, Ana Cláudia; Pestana, HelenaIntroduction Health literacy, a multidimensional concept essential to equity and the sustainability of healthcare systems, empowers individuals to make informed decisions and use services effectively, overcoming sociocultural and economic barriers. Nurse managers play a strategic role in its promotion by combining leadership with standardized nursing information systems. This article offers a reflective analysi...