3 documents found, page 1 of 1
Natural mineral-rich water ingestion by ovariectomized fructose-fed Sprague-Daw...
Das, JK; Severo, M; Pereira, CD; Patrício, E; Magalhães, J; Monteiro, R; Neves, D; Martins, MJObjective: Prevention or induction of metabolic disorders and obesity depend on estrogen signaling and/or exogenous factors, such as mineral content in diet. The protective effects of a Portuguese natural mineral-rich water against the induction of metabolic syndrome in fructose-fed male Sprague-Dawley rats have been reported. The present study was designed to assess the impact of this mineral-rich water on fru...
Ingestion of a natural mineral-rich water in an animal model of metabolic syndr...
Pereira, CD; Passos, E; Severo, M; Vito, I; Wen, X; Carneiro, F; Gomes, P; Monteiro, R; Martins, MJBACKGROUND: High-fructose and/or low-mineral diets are relevant in metabolic syndrome (MS) development. Insulin resistance (IR) represents a central mechanism in MS development. Glucocorticoid signalling dysfunction and endoplasmic reticulum (ER) and oxidative stresses strongly contribute to IR and associate with MS. We have described that natural mineral-rich water ingestion delays fructose-induced MS developm...
Role of physical exercise on hepatic insulin, glucocorticoid and inflammatory s...
Passos, E; Pereira, CD; Gonçalves, IO; Rocha-Rodrigues, S; Silva, N; Guimarães, JT; Neves, D; Ascensão, A; Magalhães, J; Martins, MJAims Pro-inflammatory mediators, glucocorticoids and transforming growth factor (TGF)-β are implicated in the pathogenesis of non-alcoholic steatohepatitis (NASH)-related insulin resistance. As physical activity is beneficial against NASH, we analyzed the voluntary physical activity (VPA) and endurance training (ET) (preventive and therapeutic strategies) effects on hepatic insulin, pro-inflammatory and glucoco...