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Gene expression of peripheral blood lymphocytes may discriminate patients with ...

Palha, Joana Almeida; Maschietto, Mariana; Silva, Aderbal R.; Puga, Renato; Lima, Leandro; Pereira, Carlos B.; Nakano, Eduardo Y.; Mello, Barbara

To identify a classifier in schizophrenia, blood gene expression profiling was applied to patients with schizophrenia under different treatments and to controls. Expression of six genes discriminated patients with sensitivity of 89.3% and specificity of 90%, supporting the use of peripheral blood as biological material for diagnosis in schizophrenia.


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