2 documents found, page 1 of 1
Therapeutic role of deep eutectic solvents based on menthol and saturated fatty...
Silva, Joana M.; Pereira, Carolina Jesus Vieira; Mano, Francisca; Silva, Eduardo; Castro, Vânia Isabel Baptista; Sá-Nogueira, Isabel; Reis, R. L.The breakthroughs achieved in green solvents promote the emergence of therapeutic deep eutectic solvents (THEDES), which possess intriguing possible applications in the biomedical field. Herein, the main aim was to unravel the biomedical potential of hydrophobic THEDES based in menthol and saturated fatty acids with different chain lengths (e.g., stearic acid (SA), myristic acid (MA), and lauric acid (LA)). Our...
Unveil the anticancer potential of limomene based therapeutic deep eutectic sol...
Pereira, Carolina Jesus Vieira; Silva, Joana M.; Rodrigues, Liliana; Reis, R. L.; Paiva, Alexandre; Duarte, Ana Rita C.; Matias, AnaDeep eutectic solvents have been recently reported as an interesting alternative to improve the therapeutic efficacy of conventional drugs, hence called therapeutic deep eutectic solvents (THEDES). The main objective of this work was to evaluate the potential of limonene (LIM) based THEDES as new possible systems for cancer treatment. LIM is known to have antitumor activity, however it is highly toxic and cell ...