4 documents found, page 1 of 1
A rare manifestation of neonatal alloimmune thrombocytopaenia
Jerónimo, M; Azenha, C; Mesquita, J; Pereira, DFNeonatal alloimmune thrombocytopaenia (NAIT) results from a fetomaternal incompatibility with maternal sensitisation against a fetal human platelet antigen (HPA) and antibodies transfer to the fetal circulation, leading to platelet destruction. The clinical presentation is variable and isolated intraocular haemorrhage is rare. We present the case of a male newborn, with intrauterine growth restriction, born at ...
Neonatal lupus with atypical cardiac and cutaneous manifestation
Morais, S; Santos, IC; Pereira, DF; Mimoso, GNeonatal lupus erythematosus is a rare, passively acquired autoimmune disease, caused by maternal autoantibodies. The most common manifestations are skin rash and congenital heart block. Cutaneous manifestations may be present at birth, but often develop within a few weeks after delivery. Congenital heart block may present as bradycardia in utero or during physical examination at birth. Approximately 40-60% of ...
Isolated anaemia as a manifestation of Rh isoimmunisation
Roda, J; Mimoso, G; Benedito, M; Pereira, DFRh isoimmunisation leads to haemolytic anaemia and hyperbilirubinaemia in the first h of life. Isolated early onset neonatal anaemia has rarely been reported. The authors describe the case of a term infant, born to an 'A' negative, second gravida mother. On the second day of life, pallor was noticed. His haemoglobin (Hb) was 6.8 g/dl, he had reticulocytosis and a positive direct antiglobulin test. However, he d...
Lessons from monochorionic twin delivery
Ferreira, SA; Januário, GM; Pereira, DF; Santos-Silva, I; Negrão, FThe presence of acute peripartum anaemia in a monochorionic twin pregnancy represents a clinical challenge requiring prompt recognition and management. Twin-to-twin transfusion syndrome (TTTS) is a major complication of these pregnancies and a medical emergency in its acute form. Acute intrapartum fetoplacental transfusion (AIFT) has been reported infrequently. The authors present a case of a probable acute TTT...