7 documents found, page 1 of 1
We vote for the person, not the policies: a systematic review on how personalit...
Falcão, Filipe; Sousa, Bárbara; Pereira, Daniela S. M.; Andrade, Renato; Moreira, Pedro; Quialheiro, Anna; Jalali, Carlos; Costa, PatrícioWestern democracies’ voting practices have altered recently, most notably with candidates now taking center stage at the expense of the institutions. These events are the result of a phenomenon called the personalisation of politics. The present review aims to synthesize evidence regarding the impact of voters’ evaluation of candidates’ traits on political outcomes and the effects of voters’ traits on voting. I...
Insights into nanomedicine for head and neck cancer diagnosis and treatment
Viegas, Cláudia Sofia; Pereira, Daniela S. M.; Fonte, PedroHead and neck cancers rank sixth among the most common cancers today, and the survival rate has remained virtually unchanged over the past 25 years, due to late diagnosis and ineffective treatments. They have two main risk factors, tobacco and alcohol, and human papillomavirus infection is a secondary risk factor. These cancers affect areas of the body that are fundamental for the five senses. Therefore, it is ...
Development of drug-loaded magneto-sensitive liposomes investigated by fluoresc...
Cardoso, Beatriz D.; Pereira, Daniela S. M.; Rodrigues, Ana Rita Oliveira; Coutinho, Paulo J. G.; Castanheira, Elisabete M. S.Magneto-sensitive liposomes can be obtained by encapsulation of magnetic nanoparticles into liposomes or by the coverage of magnetic nanoparticles with a lipid bilayer. The so-called magnetoliposomes make possible to explore the synergistic effect between chemotherapy and magnetic hyperthermia in cancer therapeutics. Both aqueous magnetoliposomes (magnetic nanoparticles entrapped in liposomes) and solid magneto...
Solid magnetoliposomes containing CaxMg1-xFe2O4 mixed ferrite nanoparticles
Cardoso, Beatriz D.; Veloso, Sérgio Rafael Silva; Pereira, Daniela S. M.; Rodrigues, Ana Rita Oliveira; Coutinho, Paulo J. G.In this work, magnetoliposomes based on superparamagnetic nanoparticles, highly promising therapeutic nanosystems for cancer therapy, were developed. The polyphenolic antitumor compound curcumin was incorporated into the lipid bilayer of the developed magnetoliposomes, considering its strong hydrophobic character, which has been a barrier to its applicability in therapeutic applications. Therefore, the magnetol...
Development of drug-loaded magneto-sensitive liposomes investigated by fluoresc...
Cardoso, Beatriz D.; Pereira, Daniela S. M.; Rodrigues, Ana Rita Oliveira; Coutinho, Paulo J. G.; Castanheira, Elisabete M. S.Magneto-sensitive liposomes can be obtained by encapsulation of magnetic nanoparticles into liposomes or by the coverage of magnetic nanoparticles with a lipid bilayer. The so-called magnetoliposomes make possible to explore the synergistic effect between chemotherapy and magnetic hyperthermia in cancer therapeutics. Both aqueous magnetoliposomes (magnetic nanoparticles entrapped in liposomes) and solid magneto...
Magnetoliposomes containing calcium ferrite nanoparticles for applications in b...
Pereira, Daniela S. M.; Cardoso, Beatriz D.; Rodrigues, Ana Rita O.; Amorim, Carlos O.; Amaral, Vítor S.; Almeida, B. G.; Queiroz, Maria João R. P.Magnetoliposomes containing calcium ferrite (CaFe<sub>2</sub>O<sub>4</sub>) nanoparticles were developed and characterized for the first time. CaFe<sub>2</sub>O<sub>4 </sub>nanoparticles were covered by a lipid bilayer or entrapped in liposomes forming, respectively, solid or aqueous magnetoliposomes as nanocarriers for new antitumor drugs. The magnetic nanoparticles were characterized by UV/Visible absorption,...
Magnetic liposomes containing calcium ferrite nanoparticles for breast cancer t...
Pereira, Daniela S. M.; Rodrigues, Ana Rita Oliveira; Almeida, B. G.; Araújo, João P.; Machado, V. A.; Queiroz, Maria João R. P.; Coutinho, Paulo J. G.In this work, calcium ferrite nanoparticles were prepared and characterized. The structural and magnetic properties of the nanoparticles were evaluated by XRD, TEM and SQUID. The synthesized nanoparticles were either entrapped in liposomes, originating aqueous magnetoliposomes (AMLs), or covered with a lipid bilayer, forming solid magnetoliposomes (SMLs). Magnetoliposomes present average diameters around 150 nm...