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Evaluating the in vitro digestion of lipids rich in medium-chain fatty acids (M...

Pereira, Ericsem; Fernandes, Jean Michel; Gonçalves, Raquel F. S.; Pinheiro, A. C.; Duarte, Maria Salomé; Alves, M. M.; Meirelles, Antonio J. A.

Investigating the digestion of lipids is paramount for developing new lipid-based products. This work evaluated the gastrointestinal (GI) digestion of medium-chain fatty acids (MCFAs) rich lipids. The dynamic GI in vitro system was used to simulate gastric, duodenal, jejunal, and ileal GI tract portions. Results from the dynamic protocol were compared against static in vitro assays and GC analyses were conducte...


In vitro digestion simulation of medium chain fatty acids

Pereira, Ericsem; Pinheiro, A. C.; Vicente, A. A.; Meirelles, António J. A.; Maximo, Guilherme J.

Gastric digestion involves physical and chemical processes, which affect food breakdown and nutrient absorption. In vitro digestion studies have been widely used to elucidate the mechanisms of food hydrolyses during digestion. They can be used to evaluate metabolic properties of macronutrients such as lipids. The gastric digestion phase is particularly crucial for digestion of medium-chain fatty acids (MCFA), f...


In vitro digestion simulation of medium chain fatty acids using static and dyna...

Pereira, Ericsem; Fernandes, Jean Michel; Gonçalves, Raquel Filipa Silva; Pinheiro, Ana Cristina; Duarte, Maria Salomé Lira; Alves, M. M.

Food biophysics research has more recently focused on understanding the behavior of foods within the human gastrointestinal (GI) tract. In vitro models allow the screening of foods and are helpful for better understanding digestive kinetics. They can be used to evaluate the metabolic properties of macronutrients such as medium-chain fatty acids (MCFAs). In this work, a dynamic GI model system [Pinheiro et al., ...


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