3 documents found, page 1 of 1
Endometriose peritoneal experimental em ratas: avaliação da dor, fertilidade, e...
Pereira, Francisco Edson Ximenes GomesEndometriosis is defined as the presence of endometrial tissue (glands and stroma) outside the uterine cavity. Objective: Evaluate the effect of the nutraceuticals omega-6/3 and omega-9/6 on pain, fertility, inflammation and oxidative stress associated with endometriosis. Methods: In this controlled experimental study, peritoneal endometriosis was induced surgically in albino Wistar rats by implanting two fragm...
Development of a subcutaneous endometriosis rat model
Pereira, Francisco Edson Ximenes Gomes; Almeida, Paulo Roberto Carvalho de; Dias, Bruno Hállan Meneses; Vasconcelos, Paulo Roberto Leitão dePURPOSE: To present a rat model of subcutaneous endometriosis for the study of pathophysiology and the effects of drugs. METHODS: Fifty three-month-old female Wistar rats (Rattus norvergicus) were distributed into one control group and four treatment groups: estradiol (2.5; 5; 10mg/kg sc), medroxyprogesterone acetate (0.5; 2; 5mg/kg sc), triptorelin pamoate (0.18; 0.56mg/kg sc) and acetylsalicylic acid (3mg/kg ...
Desenvolvimento e validação de um modelo de endometriose subcutânea em ratas pa...
Pereira, Francisco Edson Ximenes GomesEndometriosis is defined as the presence of endometrial tissue (gland and stroma) outside the uterus. The objective of this study was to design a model of subcutaneous endometriosis in rats for the evaluation of the effect of drugs and the pathophysiology of endometriosis. Initially, female Wistar rats (Rattus norvergicus) were implanted subcutaneously with 4x4 mm uterine fragments to evaluate endometrioma grow...