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Profiling of urinary extracellular vesicle protein signatures from patients wit...

Bernardino, R; Carvalho, AS; Hall, MJ; Alves, L; Leão, R; Sayyid, R; Pereira, H; Beck, HC; Campos-Pinheiro, L; Henrique, R; Fleshner, N; Matthiesen, R

Prognostic tests and treatment approaches for optimized clinical care of prostatic neoplasms are an unmet need. Prostate cancer (PCa) and derived extracellular vesicles (EVs) proteome changes occur during initiation and progression of the disease. PCa tissue proteome has been previously characterized, but screening of tissue samples constitutes an invasive procedure. Consequently, we focused this study on liqui...

Date: 2024   |   Origin: Saúde - CUF

World Heart Federation Cholesterol Roadmap: The Portuguese case

Abreu, A; Dores, H; Gonçalves, L; Franco, F; Silveira, C; Proença, G; Teresa Timóteo, A; Cardim, N; Pedro, M; Fiuza, M; Ferreira, D; Bento, L

Atherosclerotic cardiovascular disease (ASCVD) remains the major cause of premature death and disability; effective cardiovascular (CV) risk prevention is fundamental. The World Heart Federation (WHF) Cholesterol Roadmap provides a framework for national policy development and aims to achieve ASCVD prevention. At the invitation of the WHF, a group of experts from the Portuguese Society of Cardiology (SPC), addr...

Date: 2024   |   Origin: Lusíadas Saúde

Phage Display Identified Peptide with Selectivity for Human Osteoarthritic Chon...

Martins, IM; Canadas, RF; Pereira, H; Azeredo, J; Reis, RL; Oliveira, JM; Azevedo, HS

Osteoarthritis (OA) is one of the most common joint disorders in western populations, affecting millions of people worldwide and with a rising incidence as life expectancy continues to increase. Current therapies for OA management fail to halt the progressive degradation of articular cartilage, urging the need for more effective therapies to improve function and enhance quality of life. Through phage display te...


Fifteen years of coronary intravascular ultrasound in percutaneous coronary int...

Azevedo Guerreiro, R; Fernandes, R; Campante Teles, R; Canas da Silva, P; Pereira, H; Cruz Ferreira, R; Costa, M; Seixo, F; Farto E Abreu, P; Pipa, JL

INTRODUCTION: Coronary intravascular ultrasound (IVUS) is increasingly important in catheterization laboratories due to its positive prognostic impact. This study aims to characterize the use of IVUS in percutaneous coronary intervention (PCI) in Portugal. METHODS: A retrospective observational study was performed based on the Portuguese Registry on Interventional Cardiology of the Portuguese Society of Cardiol...

Date: 2020   |   Origin: Saúde - CUF

An Unexpected Association in a Patient with Heart Failure Presenting a Surgical...

Alegria, S; Simões, O; Almeida, AR; Silva e Castro, J; Laranjeira, A; Pereira, H

Bicuspid aortic valve (BAV) is the most common form of congenital heart disease and frequently leads to premature valvular dysfunction. BAV is associated with aortic wall abnormalities and a high prevalence of ascending aorta dilatation and coarctation of the aorta (CoA). Consequently, in patients with BAV a careful assessment of the valve, and also of the aortic root and the ascending aorta, should be performe...


Adjuvant antithrombotic therapy in ST-elevation myocardial infarction: Contempo...

Caldeira, D; Pereira, H; Marques, A; Alegria, S; Calisto, J; Silva, P; Ribeiro, V; Silva, JC; Seixo, F; Abreu, PF, et al.

INTRODUCTION: The standard of care for acute ST-elevation myocardial infarction (STEMI) includes the activation of a STEMI care network, the administration of adjuvant medical therapy, and reperfusion through primary percutaneous coronary intervention (PCI). While primary PCI is nowadays the first option for the treatment of patients with STEMI, antithrombotic therapy, including antiplatelet and anticoagulant a...


Quinze anos de ecografia intravascular coronária em intervenção coronária percu...

Guerreiro, R; Fernandes, R; Teles, R; Silva, P; Pereira, H; Ferreira, R; Costa, M; Seixo, F; Abreu, PF, et al.

INTRODUCTION: Coronary intravascular ultrasound (IVUS) is increasingly important in catheterization laboratories due to its positive prognostic impact. This study aims to characterize the use of IVUS in percutaneous coronary intervention (PCI) in Portugal. METHODS: A retrospective observational study was performed based on the Portuguese Registry on Interventional Cardiology of the Portuguese Society of Cardiol...


Fifteen years of coronary intravascular ultrasound in percutaneous coronary int...

Azevedo Guerreiro, R; Fernandes, R; Campante Teles, R; Canas da Silva, P; Pereira, H; Cruz Ferreira, R; Costa, M; Seixo, F; Farto E Abreu, P; Pipa, JL

INTRODUCTION: Coronary intravascular ultrasound (IVUS) is increasingly important in catheterization laboratories due to its positive prognostic impact. This study aims to characterize the use of IVUS in percutaneous coronary intervention (PCI) in Portugal. METHODS: A retrospective observational study was performed based on the Portuguese Registry on Interventional Cardiology of the Portuguese Society of Cardiol...

Date: 2019   |   Origin: Lusíadas Saúde

Thrombus aspiration in patients with ST-elevation myocardial infarction: result...

Pereira, H; Caldeira, D; Teles, R; Costa, M; Silva, P; Ribeiro, V, et al.

BACKGROUND: We aimed to evaluate the impact of thrombus aspiration (TA) during primary percutaneous coronary intervention (P-PCI) in 'real-world' settings. METHODS: We performed a retrospective study, using data from the National Registry of Interventional Cardiology (RNCI 2006-2012, Portugal) with ST-elevation myocardial infarction (STEMI) patients treated with P-PCI. The primary outcome, in-hospital mortality...


Thrombus aspiration in patients with ST-elevation myocardial infarction: result...

Pereira, H; Caldeira, D; Teles, RC; Costa, M; da Silva, PC; da Gama Ribeiro, V; Brandão, V; Martins, D; Matias, F; Pereira-Machado, F; Baptista, J

BACKGROUND: We aimed to evaluate the impact of thrombus aspiration (TA) during primary percutaneous coronary intervention (P-PCI) in 'real-world' settings. METHODS: We performed a retrospective study, using data from the National Registry of Interventional Cardiology (RNCI 2006-2012, Portugal) with ST-elevation myocardial infarction (STEMI) patients treated with P-PCI. The primary outcome, in-hospital mortality...


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