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Family visits and their involvement in patient care in intensive care units: an...

Dias Paulo Ferreira de Sousa, Diana Julia; Dias Paulo Ferreira de Sousa, Diana Julia; Ribeiro, Raquel; Jacinto, Rosa; Maia, Pedro; Moreira, Filipe

Introduction: Admission to an Intensive Care Unit (ICU) is considered a stressful phenomenon, not only due to physical issues, but also due to the cognitive and social disabilities resulting from hospitalization. The family is an important element for patients admitted to the ICU and should be a concern for nurses in these units, considering the existence of benefits for both the family and the patient. Objecti...


Egas Moniz: Nobel Prize in Medicine and Physiology

Correia Guedes, Leonor; Pereira, Isabel; Pinho e Melo, Teresa; Pavão Martins, Isabel

Date: 2025   |   Origin: SINAPSE

Randomized clinical study of injectable dextrin-based hydrogel as a carrier of ...

Machado, Alexandra; Pereira, Isabel; Costa, Filomena; Brandão, Ana; Pereira, José Eduardo; Maurício, Ana Colette; Santos, José Domingos; Amaro, Inês

This study aimed to improve the performance and mode of administration of a glass-reinforced hydroxyapatite synthetic bone substitute, Bonelike by Biosckin® (BL®), by association with a dextrin-based hydrogel, DEXGEL, to achieve an injectable and moldable device named DEXGEL Bone.; Open access funding provided by FCT|FCCN (b-on). The authors were funded by FEDER and NORTE 2020 through project no. 003262 titled ...


Dextrin hydrogel loaded with a macroporous Bonelike® scaffold and dental pulp s...

Machado, A.; Pereira, Isabel; Pereira, José Eduardo; Maltez, Luís; Brandão, Ana; Alvites, Rui; Sousa, Ana Catarina; Branquinho, Mariana

Regeneration of severe bone defects remains a challenge. A formulation of synthetic glass-reinforced hydroxyapatite bone substitute, Bonelike® Poro (BL®P), 250500 µm-diameter, with a dextrin-based hydrogel (HG), further loaded with human dental pulp stem cells (hDPSCs) with osteogenic differentiation ability, was tested for the management of critical-sized defects in an ovine model. Morphology, calcium release,...


Randomized clinical study of injectable dextrin-based hydrogel as a carrier of ...

Machado, Alexandra; Pereira, Isabel; Costa, Filomena; Brandão, Ana; Pereira, José Eduardo; Maurício, Ana Colette; Santos, José Domingos; Amaro, Inês

Objectives This study aimed to improve the performance and mode of administration of a glass-reinforced hydroxyapatite synthetic bone substitute, Bonelike by Biosckin® (BL®), by association with a dextrin-based hydrogel, DEXGEL, to achieve an injectable and moldable device named DEXGEL Bone. Methods Twelve participants requiring pre-molar tooth extraction and implant placement were enrolled in this study. BL® g...


Dextrin hydrogel loaded with a macroporous Bonelike® scaffold and dental pulp s...

Machado, Alexandra; Pereira, Isabel; Pereira, José Eduardo; Maltez, Luís; Brandão, Ana; Alvites, Rui; Sousa, Ana Catarina; Branquinho, Mariana

Regeneration of severe bone defects remains a challenge. A formulation of synthetic glass-reinforced hydroxyapatite bone substitute, Bonelike® Poro (BL®P), 250–500 µm-diameter, with a dextrin-based hydrogel (HG), further loaded with human dental pulp stem cells (hDPSCs) with osteogenic differentiation ability, was tested for the management of critical-sized defects in an ovine model. Morphology, calcium release...


Time series of counts under censoring: a Bayesian approach

Silva, Isabel; Silva, Maria Eduarda; Pereira, Isabel; McCabe, Brendan

Censored data are frequently found in diverse fields including environmental monitoring, medicine, economics and social sciences. Censoring occurs when observations are available only for a restricted range, e.g., due to a detection limit. Ignoring censoring produces biased estimates and unreliable statistical inference. The aim of this work is to contribute to the modelling of time series of counts under censo...


Thyroid Cancer Incidence in North Region of Portugal

Magno, Marisa; Rodrigues, Jéssica; Bento, Maria José; Pereira, Isabel; Freitas, Adelaide


Foreword

Silva, Fátima; Pereira, Isabel

Foreword; Nota prévia


Technical Details

Silva, Fátima; Pereira, Isabel

Technical Details; Ficha técnica


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