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Egas Moniz: Nobel Prize in Medicine and Physiology

Correia Guedes, Leonor; Pereira, Isabel; Pinho e Melo, Teresa; Pavão Martins, Isabel

Date: 2025   |   Origin: SINAPSE

Family visits and their involvement in patient care in intensive care units: an...

Dias Paulo Ferreira de Sousa, Diana Julia; Dias Paulo Ferreira de Sousa, Diana Julia; Ribeiro, Raquel; Jacinto, Rosa; Maia, Pedro; Moreira, Filipe

Introduction: Admission to an Intensive Care Unit (ICU) is considered a stressful phenomenon, not only due to physical issues, but also due to the cognitive and social disabilities resulting from hospitalization. The family is an important element for patients admitted to the ICU and should be a concern for nurses in these units, considering the existence of benefits for both the family and the patient. Objecti...


Beyond Scores: Early Findings on TBL's Impact in Engineering Education

Sena-Esteves, M. Teresa; Ribeiro, Margarida; Morais, Cristina; Brás-Pereira, Isabel; Guedes, Anabela; Soares, Filomena; Leão, Celina P.

This paper presents the preliminary findings of an ongoing study investigating the influence of Team-Based Learning (TBL) on the academic performance of engineering students, particularly its impact on their grasp of subject matter and ability to solve real-world problems. Quantitative data analysis explored correlations between students' entry-level academic scores and their performance in a course incorporati...


Revisiting Team-Based Learning in a Fluid Mechanics Module: Enhancing Students’...

Sena-Esteves, M. Teresa; Ribeiro, Margarida; Morais, Cristina; Brás-Pereira, Isabel; Guedes, Anabela; Soares, Filomena; Leão, Celina P.

This study investigates the evolution of students’ perceptions and experiences with Team-Based Learning (TBL) over three academic years (2021/22, 2022/23 and 2023/24) applied to the Fluid Mechanics course’ viscosity module of the second year of a chemical engineering degree, 1st semester. Through questionnaire data and qualitative evaluation, competences acquired and changes in teamwork and critical thinking we...


Randomized clinical study of injectable dextrin-based hydrogel as a carrier of ...

Machado, Alexandra; Pereira, Isabel; Costa, Filomena; Brandão, Ana; Pereira, José Eduardo; Maurício, Ana Colette; Santos, José Domingos; Amaro, Inês

Objectives This study aimed to improve the performance and mode of administration of a glass-reinforced hydroxyapatite synthetic bone substitute, Bonelike by Biosckin® (BL®), by association with a dextrin-based hydrogel, DEXGEL, to achieve an injectable and moldable device named DEXGEL Bone. Methods Twelve participants requiring pre-molar tooth extraction and implant placement were enrolled in this study. BL® g...


Dextrin hydrogel loaded with a macroporous Bonelike® scaffold and dental pulp s...

Machado, A.; Pereira, Isabel; Pereira, José Eduardo; Maltez, Luís; Brandão, Ana; Alvites, Rui; Sousa, Ana Catarina; Branquinho, Mariana

Regeneration of severe bone defects remains a challenge. A formulation of synthetic glass-reinforced hydroxyapatite bone substitute, Bonelike® Poro (BL®P), 250500 µm-diameter, with a dextrin-based hydrogel (HG), further loaded with human dental pulp stem cells (hDPSCs) with osteogenic differentiation ability, was tested for the management of critical-sized defects in an ovine model. Morphology, calcium release,...


Randomized clinical study of injectable dextrin-based hydrogel as a carrier of ...

Machado, Alexandra; Pereira, Isabel; Costa, Filomena; Brandão, Ana; Pereira, José Eduardo; Maurício, Ana Colette; Santos, José Domingos; Amaro, Inês

This study aimed to improve the performance and mode of administration of a glass-reinforced hydroxyapatite synthetic bone substitute, Bonelike by Biosckin® (BL®), by association with a dextrin-based hydrogel, DEXGEL, to achieve an injectable and moldable device named DEXGEL Bone.


Dextrin hydrogel loaded with a macroporous Bonelike® scaffold and dental pulp s...

Machado, Alexandra; Pereira, Isabel; Pereira, José Eduardo; Maltez, Luís; Brandão, Ana; Alvites, Rui; Sousa, Ana Catarina; Branquinho, Mariana

Regeneration of severe bone defects remains a challenge. A formulation of synthetic glass-reinforced hydroxyapatite bone substitute, Bonelike® Poro (BL®P), 250–500 µm-diameter, with a dextrin-based hydrogel (HG), further loaded with human dental pulp stem cells (hDPSCs) with osteogenic differentiation ability, was tested for the management of critical-sized defects in an ovine model. Morphology, calcium release...


Time series of counts under censoring: a Bayesian approach

Silva, Isabel; Silva, Maria Eduarda; Pereira, Isabel; McCabe, Brendan

Censored data are frequently found in diverse fields including environmental monitoring, medicine, economics and social sciences. Censoring occurs when observations are available only for a restricted range, e.g., due to a detection limit. Ignoring censoring produces biased estimates and unreliable statistical inference. The aim of this work is to contribute to the modelling of time series of counts under censo...


Thyroid Cancer Incidence in North Region of Portugal

Magno, Marisa; Rodrigues, Jéssica; Bento, Maria José; Pereira, Isabel; Freitas, Adelaide


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