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Reconciling evidence from ancient and contemporary genomes: a major source for ...

Pereira, Joana B.; Costa, Marta D.; Vieira, Daniel; Pala, Maria; Bamford, Lisa; Harich, Nourdin; Cherni, Lotfi; Alshamali, Farida; Hatina, Jiři

Important gaps remain in our understanding of the spread of farming into Europe, due partly to apparent contradictions between studies of contemporary genetic variation and ancient DNA. It seems clear that farming was introduced into central, northern, and eastern Europe from the south by pioneer colonization. It is often argued that these dispersals originated in the Near East, where the potential source genet...


A genetic chronology for the Indian Subcontinent points to heavily sex-biased d...

Silva, Marina; Oliveira, Marisa; Vieira, Daniel; Brandão, Andreia; Rito, Teresa S; Pereira, Joana B.; Fraser, Ross M.; Hudson, Bob; Gandini, Francesca

Background: India is a patchwork of tribal and non-tribal populations that speak many different languages from various language families. Indo-European, spoken across northern and central India, and also in Pakistan and Bangladesh, has been frequently connected to the so-called "Indo-Aryan invasions" from Central Asia similar to 3.5 ka and the establishment of the caste system, but the extent of immigration at ...


Phthalocyanine thio-pyridinium derivatives as antibacterial photosensitizers

Pereira, Joana B.; Carvalho, Eliana F. A.; Faustino, Maria A. F.; Fernandes, Rosa; Neves, Maria G. P. M. S.; Cavaleiro, José A. S.; Gomes, Newton C. M.

This study describes the synthesis of three new tetra- and octa-thio-pyridinium phthalocyanine derivatives. PSs 3a and 4a were prepared from the tetramerization of phthalonitriles 1 and 2, respectively, whereas PS 5 was prepared from the nucleophilic substitution of the 8 beta fluor atoms of hexadecafluorophthalocyaninatozinc(II) by mercaptopyridine, followed by cationization. The recombinant bioluminescent Esc...


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