4 documents found, page 1 of 1
IL-6 induces the overexpression of genes involved in the regulation of apoptosi...
Alves, Bárbara; Pereira, Joana F.; Ferrão, José; Vieira, Luís; Matos, Paulo; Jordan, Peter; Gonçalves, VâniaIntroduction: An inflammatory microenvironment was identified as a critical tumor-promoting condition for cells harboring tumor-initiating mutations. Cancer cells respond to pro-inflammatory signals with changes in their transcriptome, namely upregulating the expression of pro-tumorigenic transcript variants. A paradigmatic example is the variant RAC1B. We found increased RAC1B levels in samples from inflammato...
Vital Pulp Therapy in Permanent Mature Posterior Teeth with Symptomatic Irrever...
Santos, João Miguel; Pereira, Joana F.; Marques, Andréa; Sequeira, Diana B.; Friedman, ShimonBackground and Objectives: Symptomatic irreversible pulpitis in permanent mature teeth is a common indication for nonsurgical root canal treatment (NSRCT), but contemporary studies have reported on vital pulp therapy (VPT) applied in such teeth as a less invasive treatment. This systematic review assessed the outcomes of VPT, including partial and full pulpotomy performed with hydraulic calcium silicate cements...
Subcutaneous Implantation Assessment of New Calcium-Silicate Based Sealer for W...
Santos, João Miguel; Coelho, Carolina M.; Sequeira, Diana B.; Marques, Joana A.; Pereira, Joana F.; Sousa, Vítor; Palma, Paulo J.; Santos, Ana C. G.Calcium silicate-based sealers were recently introduced as a new class of endodontic sealers, with potential further benefits due to their bioactivity. The aim of this study was to evaluate the biocompatibility of two new hydraulic calcium silicate-based sealers, TotalFill BC Sealer (FKG, La Chaux-des-Fonds, Switzerland) and TotalFill BC Sealer HiFlow (FKG, La Chaux-des-Fonds, Switzerland) through subcutaneous ...
Long-Term Prognosis of Endodontic Microsurgery-A Systematic Review and Meta-Ana...
Pinto, Diogo; Marques, Andréa; Pereira, Joana F.; Palma, Paulo J.; Santos, João MiguelBackground and objectives: The long-term outcome of endodontic microsurgery (EMS) performed on root-filled teeth affected by post-treatment apical periodontitis (AP) has been a matter of debate, re-launched by the introduction of novel root-end filling materials which have been proven to improve the short-term outcome of EMS. The purpose of this systematic review and meta-analysis is to evaluate the clinical an...