8 documents found, page 1 of 1

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Achillea millefolium L. hydroethanolic extract inhibits growth of human tumor c...

Pereira, Joana M.; Peixoto, Vanessa; Teixeira, Alexandra Margarida; Sousa, Diana; Barros, Lillian; Ferreira, Isabel C.F.R.; Vasconcelos, M. Helena

Date: 2018   |   Origin: Biblioteca Digital do IPB

Melissa officinalis L. ethanolic extract inhibits the growth of a lung cancer c...

Magalhães, Daniela B.; Castro, Inês; Lopes-Rodrigues, Vanessa; Pereira, Joana M.; Barros, Lillian; Ferreira, Isabel C.F.R.; Xavier, Cristina

Melissa officinalis is a plant from the family Lamiaceae, native in Europe particularly in the Mediterranean region. Given our interest in identifying extracts and compounds capable of inhibiting tumor cell growth, and given the antioxidant content and the high consumption of Melissa officinalis in Portugal, this study aimed to test the tumor cell growth inhibitory activity of five different extracts of this pl...

Date: 2018   |   Origin: Biblioteca Digital do IPB

The cell growth inhibitory effect of an aqueous extract of Tuberaria lignosa in...

Pereira, Joana M.; Rodrigues, V.L.; Xavier, Cristina; Lima, M. João; Lima, Raquel T.; Ferreira, Isabel C.F.R.; Vasconcelos, M. Helena

Tuberaria lignosa (Sweet) Samp. is found in European regions. This plant has antioxidant properties due to its composition in ascorbic acid and phenolic compounds [1]. Given its antioxidant properties and its large traditional use, the aim of this work was to study the tumor cell growth inhibitory potential of aqueous extracts from T. lignosa (prepared by infusion and decoction). Cell growth was accessed by the...

Date: 2017   |   Origin: Biblioteca Digital do IPB

Study of the mechanism of action of Melissa officinalis L. extracts in inhibiti...

Magalhães, Daniela B.; Castro, Inês; Pereira, Joana M.; Lopes-Rodrigues, Vanessa; Ferreira, Isabel C.F.R.; Xavier, Cristina; Vasconcelos, M. Helena

Melissa officinalis L., commonly known as "lemon balm" is a perianal herbaceous plant from the family Laminaceae, native in Europe particularly in the Mediterranean region. Rosmarinic acid, the most abundant phenolic compound derived from caffeic acid, and some flavonoids such as luteolin-7-O-glucoside are described as responsible for its antimicrobial properties, antiinflammatory, antioxidant and even anti-tum...

Date: 2017   |   Origin: Biblioteca Digital do IPB

Cell growth inhibitory effect of an aqueous extract of Achillea millefolium in ...

Pereira, Joana M.; Peixoto, Vanessa; Teixeira, Alexandra Margarida; Sousa, Diana; Ferreira, Isabel C.F.R.; Vasconcelos, M. Helena

Plants used in folk medicine have increased importance in the pharmaceutical field. Achillea millefolium, also known as yarrow, is a traditional plant that can be found in Europe, Asia, North Africa and North America [1, 2]. Yarrow was shown to have antitumour, antimicrobial, antiinflammatory and antioxidant properties [3]. Indeed, several studies indicated that this plant has antioxidant potential due to its c...

Date: 2017   |   Origin: Biblioteca Digital do IPB

An aqueous extract of tuberaria lignosa inhibits cell growth, alters the cell c...

Pereira, Joana M.; Lopes-Rodrigues, Vanessa; Xavier, Cristina; Lima, M. João; Lima, Raquel T.; Ferreira, Isabel C.F.R.; Vasconcelos, M. Helena

Tuberaria lignosa (Sweet) Samp. is found in European regions, and has antioxidant properties due to its composition in ascorbic acid and phenolic compounds. Given its traditional use and antioxidant properties, the tumor cell growth inhibitory potential of aqueous extracts from T. lignosa (prepared by infusion and decoction) was investigated in three human tumor cell lines: MCF-7 (breast adenocarcinoma), NCI-H4...

Date: 2016   |   Origin: Biblioteca Digital do IPB

Antitumor activities of invasive allien species from the Azores

Bettencourt, Ana; Pereira, Joana M.; Costa, Ana C.; Seca, Ana M. L.; Barreto, Maria do Carmo

11th National Meeting of Organic Chemistry and 4th Meeting of Therapeutic Chemistry.; FRC/Azores ASMAS-M2.1.2/F/032/2011 and PREN.B/M3.1.5/I/116/2012/0000010. FCT/MEC for the financial support to the QOPNA research Unit (FCT UID/QUI/00062/2013), through national funds and where applicable co-financed by the FEDER, within the PT2020 Partnership Agreement.


Investigating the cell growth inhibitory effect of flower extracts of Sambucus ...

Lima, M. João; Pereira, Joana M.; Lima, Raquel T.; Carvalho, Ana Maria; Ferreira, Isabel C.F.R.; Vasconcelos, M. Helena

Sambucus nigra L. (elder) is widely used in traditional medicine, especially for its diuretic, antiinflammatory, diaphoretic and expectorant properties. Its rich flavonoids and ascorbic acid contents makes S. nigra flowers a good source of antioxidant compounds [1]. Nonetheless, the tumor cell growth inhibitory activity of such plant material has never been studied. Therefore, the aim of this ongoing project is...

Date: 2014   |   Origin: Biblioteca Digital do IPB

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