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Chemogenetic manipulation of astrocyte activity at the synapse- a gateway to ma...

Pereira, MJ; Ayana, R; Holt, MG; Arckens, L

Astrocytes are the major glial cell type in the central nervous system (CNS). Initially regarded as supportive cells, it is now recognized that this highly heterogeneous cell population is an indispensable modulator of brain development and function. Astrocytes secrete neuroactive molecules that regulate synapse formation and maturation. They also express hundreds of G protein-coupled receptors (GPCRs) that, on...


Measuring and mapping the effectiveness of the European Air Quality Directive i...

Serrano, HC; Oliveira, MA; Barros, C; Augusto, AS; Pereira, MJ; Pinho, P; Branquinho, C

To protect human health and the environment (namely ecosystems), international air quality protocols and guidelines, like the Gothenburg protocol (1999) and the 2001 EU Air Quality Directive (NECD), conveyed national emission ceilings for atmospheric pollutants (Directive 2001/81/EC), including the reduction of sulfur (S) and nitrogen (N) emissions by 2010. However, to what degree this expected reduction in emi...


Using nitrogen concentration and isotopic composition in lichens to spatially a...

Pinho, P; Barros, C; Augusto, S; Pereira, MJ; Máguas, C; Branquinho, C

Reactive nitrogen (Nr) is an important driver of global change, causing alterations in ecosystem biodiversity and functionality. Environmental assessments require monitoring the emission and deposition of both the amount and types of Nr. This is especially important in heterogeneous landscapes, as different land-cover types emit particular forms of Nr to the atmosphere, which can impact ecosystems distinctively...





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