15 documents found, page 1 of 2

Anti-inflammatory and antinociceptive activities of Campomanesia adamantium.

Ethnopharmacological relevance: Campomanesia species are used in folk medicine as anti-inflammatory, anti-rheumatic, anti-diarrheal and hypocholesterolemic. Aim of the study: The present study investigated the in vivo anti-inflammatory and antinociceptive properties of ethyl acetate (AE) and aqueous (Aq) extracts from leaves of Campomanesia adamantium and in vitro anti-inflammatory activity of AE and its isolated ...

Identificação e teste de toxicidade 'in vivo' do extrato bruto de cianobactéria...

Uma das consequências da utilização dos recursos hídricos em atividades desenvolvidas pelo homem é a crescente eutrofização dos ambientes aquáticos, causando o enriquecimento desses ecossistemas. Estudos toxicológicos do fitoplâncton atestam a qualidade e possibilitam o monitoramento das águas principalmente, aquelas ligadas diretamente à saúde humana. O enriquecimento da água dos pesque-pagues com nutrientes, ...

Medicamentos anti-hipertensivos utilizados na área rural de Ouro Preto, MG.

Biodegradable polymeric nanocapsules prevent cardiotoxicity of anti-trypanosoma...

Chagas disease is a neglected parasitic disease caused by the protozoan Trypanosoma cruzi. New antitrypanosomal options are desirable to prevent complications, including a high rate of cardiomyopathy. Recently, a natural substance, lychnopholide, has shown therapeutic potential, especially when encapsulated in biodegradable polymeric nanocapsules. However, little is known regarding possible adverse effects of l...

Assessment of acute toxicity of the ethanolic extract of Lychnophora pinaster (...

Species of the Lychnophora genus are plants native to Brazil, popularly known as “Brazilian arnica” and used in folk medicine as alcoholic and hydro-alcoholic preparations for the treatment of bruises, inflammation, pain, rheumatism and insect bites. The present study aimed to evaluate the safety of the use of Lychnophora pinaster Mart., Asteraceae. Acute toxicity of the crude ethanolic extract was evaluated by...

Polymeric nanocapsules prevent oxidation of core-loaded molecules : evidence ba...

Background: Nanocapsules, as a delivery system, are able to target drugs and other biologically sensitive molecules to specific cells or organs. This system has been intensively investigated as a way to protect bioactives drugs from inactivation upon interaction with the body and to ensure the release to the target. However, the mechanism of improved activity of the nanoencapsulated molecules is far from being ...

Extracts from the leaves of Campomanesia velutina inhibits production of LPS/IN...

Campomanesia velutina (Cambess) O. Berg, Myrtaceae, popularly known as “gabiroba” or “guavira”, is used in traditional Brazilian medicine to treat several diseases, including inflammation and rheumatism. Extraction and isolation from leaves of the plant afforded the active compound myricetin 3-O-rhamnoside, also known as myricitrin. The ethanolic extract of leaves of C. velutina and its ethyl acetate and methan...

Pharmacological basis for use of Lychnophora trichocarpha in gouty arthritis : ...

Ethnopharmacological relevance: The ethanolic extract of Lychnophoratrichocarpha Spreng. is used in Brazilian folk medicine to treat bruise, pain and inflammatory diseases. Aim of the study: The present study aimed at investigating whether ethanolic extract of L. trichocarpha, its ethyl acetate fraction and its main bioactive compounds could be useful to treat gouty arthritis by countering hyperuricemia and inf...

Anti-inflammatory activity of Lychnophora passerina, Asteraceae (Brazilian Arni...

Ethnopharmacological relevance: Lychnophorapasserina (Asteraceae), popularly known as “arnica,” is used to treat inflammation, pain, rheumatism, contusions, bruises and insect bites in Brazilian traditional medicine. Materials and methods: The anti-inflammatoryactivity of crude ethanolic extract of aerial parts of L. passerina and its ethyl acetate and methanolic fractions had their abilities to modulate the pr...

Prolonged cardioprotective effect of pyridostigmine encapsulated in liposomes.

Aims: The purpose of the present work was to investigate the ability of pyridostigmine encapsulated in longcirculating liposomes, to protect against ECG(electrocardiogram) alterations induced by sympathetic stimulation in rats. Main methods: The encapsulation of pyridostigmine was carried out by freeze–thaw and extrusion. Blood pressure and ECG (limb lead II) were monitored in anaesthetized male Wistar rats. Th...