65 documents found, page 1 of 7
Multidisciplinary Follow-Up After Surgical Treatment of Obesity and Metabolic D...
Preto, John; Manaças, Leonor; Pinto, Rui; Almeida, Rui; Pereira, Maria Teresa; Lazaro, André; Viveiros, Ricardo; Ferreira, André; Santos, ZéliaObesity is a growing public health problem and one of the leading causes of morbidity and mortality. Surgical treatment is the most effective approach for achieving sustained weight loss and controlling associated comorbidities; therefore, lifelong follow- up should be mandatory.The Portuguese Society for Obesity and Metabolic Diseases Surgery (SPCO) developed the present proposal for multidisciplinary follow- ...
Diagnosis and management of acromegaly: a consensus statement of the pituitary ...
Cardoso, Luís Miguel; Marques, Pedro; Pereira, Maria Teresa; Agapito, Ana; Almeida, Rui; Amaral, Sara; Cattoni, Maria Begona; Bugalho, Maria JoãoAcromegaly is characterised by hypersecretion of growth hormone and presents diagnostic and therapeutic challenges that require consensus and guidelines for effective management. The Pituitary Study Group of the Portuguese Society of Endocrinology, Diabetes and Metabolism used a modified Delphi methodology to develop consensus recommendations for the diagnosis and management of acromegaly. A multidisciplinary p...
The Paradox Between Concept Knowledge and Digital Maturity Level for Industry 4...
Guimarães, André; Pereira, Rosivaldi; Pereira, Maria Teresa; Reis, Pedro; Cardoso, Antonio J. MarquesThis study investigates the paradox between theoretical knowledge of the Industry 4.0 (I4.0) concept and the actual level of digital maturity observed in Portuguese industrial companies. Specifically, it examines whether companies’ awareness of I4.0, geographic location, and size influence their capacity to adopt and integrate digital technologies. Data were collected from a sample of 450 companies through a st...
Logistics flow improvement in a leather goods industry
Pereira, Maria Teresa; Ribeiro, João; Oliveira, Marisa; Ramos, Filipe R.; Ferreira, Fernanda A.This paper presents an optimization case study developed for a leather company, which aims to improve operational performance at the technical team level in routing and apply improvements that impact it. This project aims to create a route optimization model for what were initially intuitive routes. Since the assignment of work hours by the central team varies, there is a fluctuation in the material shipped to ...
Study of the time windows range impact on vehicle routing problem
Oliveira, Pedro Afonso; Pereira, Maria Teresa; Oliveira, Marisa; Ramos, Filipe R.; Ferreira, Fernanda A.The purpose of this chapter is to study and explain the impact of the length of the time windows in the vehicle routing problem with time windows (VRPTW). A case study was explored with the aim of understanding the relationship between the use of time windows with different intervals and the cost of charges, client satisfaction, and travel time. The solution presented studies the influence that time windows hav...
Design and implementation of a supplier Kanban system in the automotive sector:...
Pereira, Maria Teresa; Lyra, Raquel; Moreira, Miguel Ângelo Lellis; Oliveira, Marisa; Ferreira, Fernanda A.; Silva, Francisco J. G.In an increasingly competitive automotive sector subject to rapid transformation, efficient supply chain management emerges as a critical component for success. In this context, this study explores a Kanban system within an automotive supplier to address the challenges of demand variability and inventory management. Employing an Action Research methodology, the case study unfolds four iterations, each advancing...
Six-Year Complete Remission of Type-1 Diabetes Mellitus in an Adult Treated Wit...
Benido Silva, Vânia; Pereira, Maria TeresaA "honeymoon" phase is a transient period of type 1 diabetes (T1D) remission, characterized by a significant reduction in insulin requirements and good glycemic control due to a temporary restoration of pancreatic β-cell function. This phenomenon occurs in about 60% of adults with this disease, is usually partial, and lasts for up to 1 year. We present a case of a 6-year complete remission of T1D in a 33-year-o...
Iatrogenic Cushing’s Syndrome: The Result of Cobicistat and Glucocorticoid Inte...
Benido Silva, Vânia; Cardoso, Joana; Esteves Brandão, Maria; Mesquita, Isabel; Pereira, Maria TeresaCobicistat, used as a pharmacokinetic booster in therapeutic combination with human immunodeficiency virus (HIV) protease inhibitors and integrase inhibitors, is a strong inhibitor of cytochrome P450 3A4 (CYP3A4). Since most glucocorticoids are metabolized by the isoenzyme of the cytochrome P450 pathway, their plasma concentrations can be highly increased in the presence of cobicistat-boosted darunavir, with su...
Analysis of pharmacy and laboratory reagents stock management in a Portuguese p...
Sequeiros, José; Pereira, Maria Teresa; Oliveira, Marisa; Ferreira, Fernanda A.The current situation of healthcare units is characterised by the increasing cost of providing the respective care, the consequent deterioration of the financial situation, and the complicated and time-consuming processes. Together with rising demand, they may become factors contributing to a decrease in service demand. Due to this situation, more efficient and effective logistics and supply chain management ar...
Continuous improvement of logistics processes in a production line of electric ...
Gomes, Beatriz Especial; Pereira, Maria Teresa; Oliveira, Marisa; Ferreira, Fernanda A.Nowadays, environmental concerns are deeply rooted in our society. This growing concern is reflected in the strategies implemented by organizations, which are increasingly focused on eco-friendly strategies, not only for its strategic aspect but also for its social responsibility. Therefore, a bus manufacturing company and an automotive company, both located in the north of Portugal, followed this trend by acti...