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Bioinformatic Approach to Unveil Key Differentially Expressed Proteins in Human...

Corda, Pedro O.; Silva, Joana Vieira; Pereira, Sara C.; Barros, Alberto; Alves, Marco G .; Fardilha, Margarida

Currently, two conventional freezing techniques are used in sperm cryopreservation: slow freezing (SF) and rapid freezing (RF). Despite the protocolar improvements, cryopreservation still induces significant alterations in spermatozoon that are poorly understood. Here, available proteomic data from human cryopreserved sperm was analyzed through bioinformatic tools to unveil key differentially expressed proteins...


Lifestyle, metabolic disorders and male hypogonadism - a one-way ticket?

Crisóstomo, Luís; Pereira, Sara C.; Monteiro, Mariana P.; Raposo, João F.; Oliveira, Pedro F.; Alves, Marco G.

Hypogonadism is more frequent among men with common metabolic diseases, notably obesity and type 2 diabetes. Indeed, endocrine disruption caused by metabolic diseases can trigger the onset of hypogonadism, although the underlying molecular mechanisms are not entirely understood. Metabolic diseases are closely related to unhealthy lifestyle choices, such as dietary habits and sedentarism. Therefore, hypogonadism...


Laparoscopic gastropexy in neonatal gastric volvulus

Vital, Vanda P.; Pereira, Sara C.; Henriques, João M.; Casella, Paolo

Introduction: Gastric volvulus is a rare condition in pediatric age. Acute and recurrent chronic cases are described but the real incidence is unknown. We present the surgical description of a case of a chronic recurrent gastric volvulus, diagnosed in the neonatal period and treated with success by laparoscopy. Clinical case: Newborn, male, diagnosed with Ebstein anomaly, admitted in the hospital with recurrent...

Date: 2012   |   Origin: Revista Portuguesa de Cirurgia

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