Introdução e objetivos: A doença arterial periférica (DAP) é uma manifestação comum da aterosclerose e representa um indicador significativo de risco cardiovascular, afetando a qualidade de vida dos doentes devido à claudicação e, em estadios avançados, a lesões tróficas, sendo a principal causa não-traumática de amputação dos membros inferiores. A Diabetes Mellitus é um dos principais fatores de risco para DAP...
This study presents a detailed geomorphological and geochronological analysis of a marine terrace staircase developed into the Peniche Peninsula (Portugal), a rocky headland of Jurassic carbonate bedrock located in the central sector of the Western Iberian passive margin. The marine terrace levels are described morphologically and sedimentologically, but also dated using ESR and U-Series methodologies. The mari...
Background/Objectives: Neurocognitive disorders (NCDs) encompass a spectrum of conditions that significantly impact cognitive domains, including attention, memory, and language. Mild NCD, increasingly prevalent with aging, represents an early stage of these disorders, characterized by cognitive deficits that do not interfere with daily functioning. Non-pharmacological therapies, especially cognitive stimulation...
This short report presents newly discovered Palaeolithic rock art panels within the Ocreza Valley (Lower Tejo River), central Portugal, comprising several engraved zoomorphic figures, including auroch and horse. Together, they substantially increase upon the previous headless horse found in 2000, and the style of the engravings is identical to Upper Palaeolithic open-air engravings from other areas of western I...
Sodium, although essential for life, is a key factor in changes in vascular function and cardiovascular disease when consumed in excess. Sarcocornia spp., a halophyte plant with many nutritional benefits, presents itself as a promising substitute for the consumption of purified salt. Matrix metalloproteinases (MMPs) 2 and 9 are widely studied due to their action in physiological processes and as biomarkers at t...
Introduction:Sleep is vital for health as it has regenerative and protective functions. During sleep, there is a cyclicity of different phases that are analysed and classified for clinical purposes using polysomnography (PSG), a costly and technically demanding method. The tremendous growth of sleep medicine, where demand for studies far outstrips supply, opens a window for the development of accurate, low-thre...
Abstract: In recent years, the world’s aging population has increased, contributing to the development of age-related pathologies, which have been aggravated by physical inactivity and excessive fat intake. This study aimed to evaluate the effect of implementing a nutritional program (control group—CG) combined with exercise (intervention group—IG) on the inflammatory profile, MMPs, and TIMPs in a group of 34 e...
Atrial fibrillation (AF), the most common cardiac arrhythmia, is associated with adverse CV outcomes. Vascular aging (VA), which is defined as the progressive deterioration of arterial function and structure over a lifetime, is an independent predictor of both AF development and CV events. A timing identification and treatment of early VA has therefore the potential to reduce the risk of AF incidence and relate...
Introduction: Congenital heart diseases are one of the leading causes of children mortality worldwide. Due to inadequate access to paediatric cardiac surgical care, the burden of these anomalies is even higher in low and middle-low-income countries. Objective: To comprehensively describe the access to paediatric cardiac surgical care in low and middle-low-income countries, highlighting existing disparities and ...