104 documents found, page 1 of 11
N-Succinylated canonical vs. dehydropeptides: contrasting self-assembly pathway...
Pereira, Teresa; Carvalho, André F.; Teixeira, Filipe; Magalhães, Andreia Patrícia; Pereira, David M.; Hilliou, L.; Abrunhosa, AnteroLimited mechanical robustness and prompt proteolytic degradation preclude wider biomedical application of supramolecular peptide hydrogels. Low-molecular-weight dehydropeptides represent a promising class of hydrogelators, owing to their enhanced proteolytic stability, high self-assembly propensity, biocompatibility, and tunable rheological and drug-release properties. Herein, we prepared a small library of N-s...
Tripeptides featuring dehydrophenylalanine and homophenylalanine: homo- versus ...
Carvalho, André F.; Pereira, Teresa; Oliveira, Carlos; Figueiredo, Pedro; Carvalho, Alexandra; Pereira, David M.; Hilliou, L.; Bañobre-López, ManuelOver the years, our research group developed dehydrodipeptides N-capped with aromatic moieties as protease-resistant efficacious hydrogelators, affording self-assembled hydrogels at low (critical) concentrations. Dehydrotripeptides, with different dipeptide sequences and (D,L) stereochemistry, open a wider chemical space for the development of self-assembled soft nanomaterials. In this work, a small library of ...
Endoscopic Sleeve Gastroplasty as Facilitatorfor Renal Transplantation in Patie...
Patrício Correia, Vítor; Pereira, Teresa; Miranda, Carlos; Lalanda, Raquel; Nogueira, Helena Filipa; Marques, Pedro; Costa Gomes, Olavo; Craciun, AnaIntroduction: Obesity is a major barrier to kidney transplantation, associated with increased perioperative complications and reduced graft survival. Traditional bariatric surgeries have shown effectiveness in weight reduction but present challenges in pharmacokinetics and nutritional status. Endoscopic sleeve gastroplasty has emerged as a less invasive alternative, potentially suitable as a bridge to renal tra...
Industry 4.0 in Portugal: Validation of a Readiness Assessment Model Through an...
Guimarães, André; Reis, Pedro; Pereira, Teresa; Antonio J. Marques CardosoPurpose – Industry 4.0 requires businesses to adapt strategically and continuously assess their readiness. However, many manufacturing companies struggle to evaluate and implement Industry 4.0 due to the lack of clear assessment frameworks. This study addresses this gap by applying a structured maturity model to assess Industry 4.0 readiness in Portuguese companies. Design/methodology/approach – The study usest...
Exploring the factor structure of criminogenic cognitions in incarcerated males...
Pereira, Teresa; Oliveira, Catarina; Basto Pereira, MiguelDespite the importance of criminogenic thinking in addressing criminal behavior, validated instruments to measure these cognitions in Portuguese forensic settings are scarce. Therefore, the main aim of this study was to explore the psychometric properties of the Criminogenic Cognitions Scale (CCS) in a sample of 364 Portuguese incarcerated males (Mage = 37.88, SD = 10.88). An exploratory factor analysis was con...
Brief History of European Surgery: A Coloproctology Perspective
Borges, Eva; Ferreira, Carlos; Fernandes , Sara; Silva, Fabiana; Spínola de Almeida, Catarina; Ângelo, Miguel; Jordão, Daniel; Pereira, TeresaThe field of colorectal surgery has evolved over the millennia, shaped by the continuous interplay of cultural values, anatomical discoveries, and technological advances. From the ancient Egyptian papyri that detailed anorectal conditions and therapeutic enemas to the empirical innovations of Greek and Roman physicians, the early approach to surgery was curious yet pragmatic. Although classical medicine introdu...
Effects of Lean Tools and Industry 4.0 technology on productivity: An empirical...
Guimarães, André; Oliveira, Eduardo e; Oliveira, Marisa; Pereira, TeresaPurpose: In the 4th Industrial Revolution era, companies are increasingly adopting strategies to maximize the potential of Industry 4.0 technologies. Many organizations integrate established Lean and Six Sigma tools to support the effective deployment of these innovations. Although existing literature explores the interplay between Industry 4.0 and Lean methodologies, there is limited focus on their direct impa...
AI-Powered Data Management to Optimize Data Collection and Processing in a Pain...
Pereira, Teresa; Oliveira, Marisa; Tavares, Miguel; Guimarães, AndréIndustrial laboratories often remain under-digitized compared to production lines, creating a gap between data acquisition and analytical intelligence, critical for advanced quality control. This study addresses this gap by proposing and validating a novel framework that combines Low-Code digitalisation tools with Machine Learning (ML) and Causal Inference to optimise data collection and analysis in an automoti...
The Postapocalyptic Frontier Hero
Pereira, TeresaThe following article argues that Naughty Dog's The Last of Us is a Weird Western that, despite imaginatively reinventing the Western genre by setting it in a near-future, postapocalyptic United States, reiterates many of its core tenets. Among these are the inclusion of a cowboy-like, white, male hero, namely the game's protagonist, Joel Miller, and the depiction of gruesome violence as both regenerative and j...
Os meninos que conhecem líquenes e abraçam árvores
Nobre, Alexandra; Pereira, TeresaEsta história, como quase todas, começa com um acaso. De Jul a Out, o Centro Ciência Viva da Floresta (CCVF) teve patente a exposição, “Líquenes, a beleza da simbiose” (STOL/DBio-UMinho). Nesse âmbito, convidou uma das autoras para um Café de Ciência e, “já agora”, o “Encontro com um cientista” da Escolinha Ciência Viva. Era a vez da turma P9 da EB de Proença-a-Nova (PaN) constituída por 17 crianças (4º ano) e ...