Background: Patients with obstructive sleep apnea syndrome (OSAS), undergoing treatment with continuous positive airway pressure (CPAP), after discharge from the hospital consultation, should maintain follow-up in primary health care, for therapeutic monitoring. Objectives: To improve the follow-up of patients with OSAS with CPAP and without sleep medicine consultation follow-up, in a Family Health Unit (FHU). ...
Anti-glomerular basement membrane (anti-GBM) disease is an aggressive small vessel vasculitis usually mediated by IgG autoantibodies. We describe the case of a 73-year-old male with rapidly progressive renal failure that was diagnosed with IgA mediated anti-GBM disease associated with circulating anti-neutrophil cytoplasm antibodies (ANCA), where the diagnosis was established on kidney biopsy by detecting linea...
Introduction: Transthoracic biopsies under fluoro-computer tomography (CT) guidance play an important role on the diagnosis and management of lung nodules, permitting histological examination and differentiation between benign and malignant lesions(1). Furthermore, with recent advances in target therapy, it is increasingly necessary to obtain tumor tissue for the analysis of molecular fingerprints allowing pers...
Introduction: Mental illness stigma studies demonstrate the presence of stigmatizing attitudes towards people with mental illness both by the public and health professionals. This study aimed to analyze the attitudes of professionals working at a Portuguese psychiatric hospital towards people with mental illness. Material and Methods: A cross‑sectional observational study was conducted to examine the attitudes ...
In this work, we explore the potential of deep learning to streamline the process of identifying new potential drugs through the computational generation of molecules with interesting biological properties. Two deep neural networks compose our targeted generation framework: the Generator, which is trained to learn the building rules of valid molecules employing SMILES strings notation, and the Predictor which e...
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Background: Patients under dialysis have a high cardiovascular risk and they are at increased risk when submitted to cardiac surgery. Aim of the study: to evaluate morbidity, early and late mortality, and predictive factors of mortality in patients under dialysis who underwent cardiac surgery. Methods: A retrospective observational study was performed including all dialysis dependent patients who underwent card...
Este artigo visa o estudo do impacto do petróleo no crescimento económico dos países do Médio Oriente e do Norte de África. A investigação sobre este tema surgiu da necessidade de responder se de facto, a produção de petróleo é determinante ou não no crescimento económico dos países que se dedicam a esta atividade. Também pretendemos perceber como estes países dotados da maior fonte de riqueza, da qual todos os...
The concept of Precision Agriculture is usually associated with the usage of high-end technology equipment (hardware or software) to evaluate or monitor the conditions of a determined portion of land, adjusting afterwards the production factors, like seeds, fertilizers, pesticides, growing regulators, water, according to differential detected characteristics. This paper describes an algorithm developed to analy...