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Extraradicular infection and apical mineralized biofilm: a systematic review of...

Pérez, Alejandro R.; Rendón, Jaime; Ortolani-Seltenerich, P. S.; Pérez-Ron, Yetzangel; Cardoso, Miguel; Noites, Rita; Loroño, Gaizka; Vieira, Gaya C. S.

Background/Objectives: Bacterial biofilms on root surfaces outside the apical foramen are linked to refractory apical periodontitis, as microorganisms can survive in extraradicular areas and cause persistent infections. This study aimed to precisely evaluate the relationship between extraradicular biofilm and persistent periapical periodontitis through an overview of case reports. Methods: A systematic search o...


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