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Naive and stem cell memory T cell subset recovery reveals opposing reconstituti...

Soares, Maria Vieira; Azevedo, Rita I.; Ferreira, Ines; Bucar, Sara; Ribeiro, Ana C.; Vieira, Ana I. S.; Pereira, Paulo N G; Ribeiro, Ruy M.

The success of allogeneic hematopoietic stem cell transplantation (allo-HSCT) in the treatment of hematological malignancies remains hampered by life-threatening chronic graft vs. host disease (cGVHD). Although multifactorial in nature, cGVHD has been associated with imbalances between effector and regulatory T cells (Treg). To further elucidate this issue, we performed a prospective analysis of patients underg...


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