5 documents found, page 1 of 1
Molecular diagnosis of invasive aspergillosis in a child with clinical suspicio...
Sabino, Raquel; Ramos, A.; Simões, H.; Palaré, M.J.; Moreno, R.; Ferrão, A.; Lourenço, F.; Marques, J.G.; Martins, C.; Morais, A.; Verissimo, C.Purpose: Invasive aspergillosis is difficult to manage in immunocompromised patients. We present a clinical case of a 13-year-old boy from Cabo Verde who was transferred to the Hematology Unit of a Central Hospital in Lisbon, Portugal, and diagnosed with aplastic anemia. Weeks after hospital admission, in June 2016, he presented febrile neutropenia with negative blood cultures. In August, the patient showed a n...
Evaluation of Nanoparticle Uptake iii Co-culture Cancer Modeis
Costa, C.E.; Gaspar, V.M.; Marques, J.G.; Coutinho, Paula; Correia, I. J.Co-culture models are currently bridging the gap between classical cultures and in vivo animal models. Exploring this novel approach unlocks the possibility to mimic the tumor microenvironment in vitro, through the establishment of cancer-stroma synergistic interactions. Notably, these organotypic models offer a perfect platform for the development and pre-clinical evaluation of candidate nanocarriers loaded wi...
Radiation damage formation and annealing in GaN and ZnO
Lorenz, K.; Peres, M.; Franco, N.; Marques, J.G.; Miranda, S.M.C.; Magalhães, S.; Monteiro, T.; Wesch, W.; Alves, E.; Wendler, E.The radiation damage formation upon low temperature ion implantation and neutron irradiation has been compared for GaN and ZnO. Both materials exhibit strong dynamic annealing effects during implantation, even at 15 K, leading to high amorphisation thresholds. The damage build-up with fluence was found to proceed in a similar way for GaN and ZnO, both showing two saturation regimes below the amorphisation level...
Vasculitis-like syndrome associated with Borrelia lusitaniae infection
Lopes de Carvalho, Isabel; Fonseca, J.E.; Marques, J.G.; Ullmann, A.; Hojgaard, A.; Zeidner, N.; Núncio, M.S.We report the isolation of Borrelia lusitaniae from a 13-year-old female child presenting with a vasculitis syndrome. The patient was treated with doxycycline, 100 mg bid for 20 days, and is in remission after a follow-up of 2 years. These results should alert clinicians to the fact that B. lusitaniae may be pathogenic in humans, highlighting that patients may be seronegative or present with minimal positive an...
Defect studies on fast and thermal neutron irradiated GaN
Lorenz, K.; Marques, J.G.; Franco, N.; Alves, E.; Peres, M.; Correia, M.R.; Monteiro, T.Single crystalline epitaxial GaN films were irradiated with fast (E > 1 MeV) or with fast and thermal neutrons. These irradiation conditions allow the separation of the effect of transmutational doping with Ge due to nuclear reactions with thermal neutrons on the damage production. High resolution X-ray diffraction showed an expansion of the c-lattice parameter after irradiation which is reversed after annealin...