4 documents found, page 1 of 1
Reuma.pt/vasculitis : the Portuguese vasculitis registry
Ponte, Cristina; Khmelinskii, Nikita; Teixeira, Vítor; Luz, Karine; Peixoto, Daniela; Rodrigues, Marília; Luís, Mariana; Teixeira, Lídia; Sousa, SandraBackground: The vasculitides are a group of rare diseases with different manifestations and outcomes. New therapeutic options have led to the need for long-term registries. The Rheumatic Diseases Portuguese Register, Reuma.pt, is a web-based electronic clinical record, created in 2008, which currently includes specific modules for 12 diseases and > 20,000 patients registered from 79 rheumatology centres. On Oct...
Localized Pigmented Villonodular Synovitis of the Shoulder: a Rare Presentation...
Madruga Dias, João; Costa, Maria Manuela; Duarte, Artur; Pereira da Silva, José A.Pigmented Vilonodular Synovitis is a rare clinical entity characterized as a synovial membrane benign tumour, despite possible aggressive presentation with articular destruction. The localized variant is four times less frequent and the shoulder involvement is uncommon. We present the case of a Caucasian 59 year-old patient, who presented with left shoulder pain, of uncharacteristic quality, with local swelling...
BioRePortAP, an electronic clinical record coupled with a database : an example...
Campanilho-Marques, R.; Polido-Pereira, J.; Rodrigues, A.; Ramos, F.; Saavedra, M. J.; Costa, M.; Martins, F.; Pereira da Silva, José A.; Canhao, HelenaAims: To evaluate the efficacy and safety of the treatment of psoriatic arthritis (PsA) patients with tumor necrosis factor (TNF) antagonists in the Rheumatology Department of Hospital de Santa Maria using the BioRePortAP. Methods: The Portuguese Society of Rheumatology (SPR) developed an electronic medical chart coupled with a database for the follow up of PsA patients, the BioRePortAP, which was launched in M...
Monoclonal anti-CD8 therapy induces disease amelioration in the K/BxN mouse mod...
Raposo, Bruno R.; Rodrigues-Santos, Paulo; Carvalheiro, Helena; Água-Doce, Ana M.; Carvalho, Lina; Pereira da Silva, José A.; Graça, LuísObjective. CD8+ T cells are part of the T cell pool infiltrating the synovium in rheumatoid arthritis (RA). However, their role in the pathogenesis of RA has not been fully delineated. Using the K/BxN mouse model of spontaneous chronic arthritis, which shares many similarities with RA, we studied the potential of CD8 T cell depletion with monoclonal antibodies (mAb) to stop and reverse the progression of experi...